Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems

Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of systems based on colloidal particles as vehicles for the delivery of the anticancer drug 5-fluorouracil have been devised. The target is always to provide the proper dose of the antitumor agent only at...

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Detalles Bibliográficos
Autor principal: Arias, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245407/
https://www.ncbi.nlm.nih.gov/pubmed/18830159
http://dx.doi.org/10.3390/molecules13102340
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author Arias, José L.
author_facet Arias, José L.
author_sort Arias, José L.
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description Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of systems based on colloidal particles as vehicles for the delivery of the anticancer drug 5-fluorouracil have been devised. The target is always to provide the proper dose of the antitumor agent only at the desired locus of action, thus reducing the unwanted side effects. In this review, the main strategies and the more significant results in the development of 5-fluorouracil carriers for cancer treatment are discussed.
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spelling pubmed-62454072018-11-30 Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems Arias, José L. Molecules Review Because of the fundamental importance of new therapeutic routes for cancer treatment, a number of systems based on colloidal particles as vehicles for the delivery of the anticancer drug 5-fluorouracil have been devised. The target is always to provide the proper dose of the antitumor agent only at the desired locus of action, thus reducing the unwanted side effects. In this review, the main strategies and the more significant results in the development of 5-fluorouracil carriers for cancer treatment are discussed. MDPI 2008-10-01 /pmc/articles/PMC6245407/ /pubmed/18830159 http://dx.doi.org/10.3390/molecules13102340 Text en © 2008 by the authors. Licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Arias, José L.
Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
title Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
title_full Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
title_fullStr Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
title_full_unstemmed Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
title_short Novel Strategies to Improve the Anticancer Action of 5-Fluorouracil by Using Drug Delivery Systems
title_sort novel strategies to improve the anticancer action of 5-fluorouracil by using drug delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245407/
https://www.ncbi.nlm.nih.gov/pubmed/18830159
http://dx.doi.org/10.3390/molecules13102340
work_keys_str_mv AT ariasjosel novelstrategiestoimprovetheanticanceractionof5fluorouracilbyusingdrugdeliverysystems

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