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Docking Studies and Anti-inflammatory Activity of β-Hydroxy-β-arylpropanoic Acids

The article describes a two-step synthesis of diastereomeric 3-hydroxy-2-methyl-3-(4-biphenylyl)butanoic acids. In the first step an intermediate α-bromo propanoic acid 1-ethoxyethyl ester was synthesized. The second step is a new modified Reformatsky reaction in presence of Zn in tetrahydrofuran (T...

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Detalles Bibliográficos
Autores principales: Dilber, Sanda P., Dobric, Silva Lj., Juranic, Zorica D., Markovic, Bojan D., Vladimirov, Sote M., Juranic, Ivan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245448/
https://www.ncbi.nlm.nih.gov/pubmed/18463569
http://dx.doi.org/10.3390/molecules13030603