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AMPK-dependent and independent actions of P2X7 in regulation of mitochondrial and lysosomal functions in microglia

BACKGROUND: P2X7 is ubiquitously expressed in myeloid cells and regulates the pathophysiology of inflammatory diseases. Since mitochondrial function in microglia is highly associated with microglial functions in controlling neuronal plasticity and brain homeostasis, we interested to explore the role...

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Detalles Bibliográficos
Autores principales:	Sekar, Ponarulselvam, Huang, Duen-Yi, Hsieh, Shie-Liang, Chang, Shwu-Fen, Lin, Wan-Wan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245559/ https://www.ncbi.nlm.nih.gov/pubmed/30458799 http://dx.doi.org/10.1186/s12964-018-0293-3

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