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Saccharomyces cerevisiae adapted to grow in the presence of low-dose rapamycin exhibit altered amino acid metabolism

BACKGROUND: Rapamycin is a potent inhibitor of the highly conserved TOR kinase, the nutrient-sensitive controller of growth and aging. It has been utilised as a chemotherapeutic agent due to its anti-proliferative properties and as an immunosuppressive drug, and is also known to extend lifespan in a...

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Detalles Bibliográficos
Autores principales:	Dikicioglu, Duygu, Dereli Eke, Elif, Eraslan, Serpil, Oliver, Stephen G., Kirdar, Betul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245637/ https://www.ncbi.nlm.nih.gov/pubmed/30458881 http://dx.doi.org/10.1186/s12964-018-0298-y

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