Cargando…

Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study

BACKGROUND: Risperidone is mainly metabolized by cytochrome P450 (CYP) 2D6 in the liver. The gene encoding CYP2D6 is highly polymorphic. The average steady-state plasma concentration of risperidone active moiety is higher in the CYP2D6 intermediate metabolizers (IMs) compared with that in the extens...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ito, Takahiro, Yamamoto, Kazuhiro, Ohsawa, Fuminori, Otsuka, Ikuo, Hishimoto, Akitoyo, Sora, Ichiro, Hirai, Midori, Yano, Ikuko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245770/ https://www.ncbi.nlm.nih.gov/pubmed/30479825 http://dx.doi.org/10.1186/s40780-018-0126-y

Ejemplares similares

PM311. Possible role of CDH13 in nicotine dependence: Investigations on mouse neural progenitors and schizophrenia patients
por: Otsuka, Ikuo, et al.
Publicado: (2016)

Investigation of chromosome Y loss in men with schizophrenia
por: Hirata, Takashi, et al.
Publicado: (2018)

Association of Two Variable Number of Tandem Repeats in the Monoamine Oxidase A Gene Promoter with Schizophrenia
por: Tanifuji, Takaki, et al.
Publicado: (2021)

Epigenetic clock analysis of blood samples from Japanese schizophrenia patients
por: Okazaki, Satoshi, et al.
Publicado: (2019)

Association analysis of the Cadherin13 gene with schizophrenia in the Japanese population
por: Otsuka, Ikuo, et al.
Publicado: (2015)

Decelerated epigenetic aging associated with mood stabilizers in the blood of patients with bipolar disorder
por: Okazaki, Satoshi, et al.
Publicado: (2020)

Searching for biomarkers in schizophrenia and psychosis: Case‐control study using capillary electrophoresis and liquid chromatography time‐of‐flight mass spectrometry and systematic review for biofluid metabolites
por: Kim, Saehyeon, et al.
Publicado: (2021)

Physiologically‐based pharmacokinetic model to investigate the effect of pregnancy on risperidone and paliperidone pharmacokinetics: Application to a pregnant woman and her neonate
por: Mahdy, Walaa Y. B., et al.
Publicado: (2023)

A cross-sectional study exploring useful indicators for low bone mineral density in male alcoholic patients
por: Horai, Tadasu, et al.
Publicado: (2018)

Ribosomal DNA gene copies are increased in blood and brain of Japanese schizophrenia patients
por: Li, Sen, et al.
Publicado: (2023)

Telencephalon Organoids Derived from an Individual with ADHD Show Altered Neurodevelopment of Early Cortical Layer Structure
por: Zhang, Danmeng, et al.
Publicado: (2023)

Loss of chromosome Y in blood, but not in brain, of suicide completers
por: Kimura, Atsushi, et al.
Publicado: (2018)

Association study of MIF promoter polymorphisms with suicide completers in the Japanese population
por: Shimmyo, Naofumi, et al.
Publicado: (2017)

RISPERIDONE IN SCHIZOPHRENIA
por: Agashe, Mohan, et al.
Publicado: (1999)

RISPERIDONE IN SCHIZOPHRENIA
por: Kumar, P.N. Suresh
Publicado: (1999)

Epigenetic clock analysis and increased plasminogen activator inhibitor-1 in high-functioning autism spectrum disorder
por: Okazaki, Satoshi, et al.
Publicado: (2022)

Polymorphisms in the hypoxia inducible factor binding site of the macrophage migration inhibitory factor gene promoter in schizophrenia
por: Okazaki, Satoshi, et al.
Publicado: (2022)

Aberrant telomere length and mitochondrial DNA copy number in suicide completers
por: Otsuka, Ikuo, et al.
Publicado: (2017)

Olanzapine/risperidone: Sedation, increased cholesterol levels and extrapyramidal side-effects in the form of akathisia: 3 case reports
Publicado: (2021)

Accelerated epigenetic age and shortened telomere length based on DNA methylation in Nicolaides–Baraitser syndrome
por: Shinko, Yutaka, et al.
Publicado: (2022)

Rare compound heterozygous missense SPATA7 variations and risk of schizophrenia; whole-exome sequencing in a consanguineous family with affected siblings, follow-up sequencing and a case-control study
por: Igeta, Hirofumi, et al.
Publicado: (2019)

RISPERIDONE IN INDIAN PATIENTS WITH SCHIZOPHRENIA
por: Duggal, Harpreet S., et al.
Publicado: (1999)

RISPERIDONE IN INDIAN PATIENTS WITH SCHIZOPHRENIA
por: Agarwal, A.K., et al.
Publicado: (1998)

PM322. The risk factors of low bone mineral density in male alcoholic patients: cross-sectional study
por: Horai, Tadasu, et al.
Publicado: (2016)

Accelerated epigenetic aging and decreased natural killer cells based on DNA methylation in patients with untreated major depressive disorder
por: Shindo, Ryota, et al.
Publicado: (2023)

Economic Burden Associated with Extrapyramidal Symptoms in a Medicaid Population with Schizophrenia
por: Abouzaid, Safiya, et al.
Publicado: (2012)

Extrapyramidal side effects in first-episode schizophrenia treated with flupenthixol decanoate
por: Joubert, Francois-Pierre, et al.
Publicado: (2021)

Genetic Polymorphisms in CYP2E1: Association with Schizophrenia Susceptibility and Risperidone Response in the Chinese Han Population
por: Huo, Ran, et al.
Publicado: (2012)

ONCE DAILY RISPERIDONE IN TREATMENT OF SCHIZOPHRENIA
por: Agarwal, Vivek, et al.
Publicado: (2001)

COMPARATIVE EFFICACY OF CENTBUTINDOLE & RISPERIDONE IN SCHIZOPHRENIA
por: Chandra, R., et al.
Publicado: (2002)

Risperidone Associated Paralytic Ileus in Schizophrenia
por: Ramamourthy, Parthasarathy, et al.
Publicado: (2013)

PM402. Factors associated with sexual health in Korean patients with schizophrenia receiving risperidone monotherapy
por: Lee, Ju-Yeon, et al.
Publicado: (2016)

Treatment Discontinuation Among Patients with Schizophrenia Treated with Brexpiprazole and Other Oral Atypical Antipsychotics in Japan: A Retrospective Observational Study
por: Hishimoto, Akitoyo, et al.
Publicado: (2022)

Genome-wide association studies identify polygenic effects for completed suicide in the Japanese population
por: Otsuka, Ikuo, et al.
Publicado: (2019)

CYP2D6 polymorphisms and their influence on risperidone treatment
por: Puangpetch, Apichaya, et al.
Publicado: (2016)

Mitochondrial DNA Copy Number Raises the Potential of Left Frontopolar Hemodynamic Response as a Diagnostic Marker for Distinguishing Bipolar Disorder From Major Depressive Disorder
por: Tsujii, Noa, et al.
Publicado: (2019)

PM451. A decrease in protein level and a missense polymorphism of KIF17 are associated with schizophrenia
por: Hishimoto, Akityo, et al.
Publicado: (2016)

Erratum: Extrapyramidal side effects in first-episode schizophrenia treated with flupenthixol decanoate
por: Joubert, Francois-Pierre, et al.
Publicado: (2021)

Clinical utility of the risperidone formulations in the management of schizophrenia
por: Madaan, Vishal, et al.
Publicado: (2011)

Long-lasting extrapyramidal symptoms after multiple injections of paliperidone palmitate to treat schizophrenia
por: Takada, Ryohei, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_54upmu9n4875pgfgsmrkmr7bba