Cargando…

Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb

BACKGROUND: Melanoma, the most aggressive form of skin cancer, is characterized by high rates of metastasis, drug resistance and mortality. Here we investigated the role of Semaphorin 5A (Sema5A) on the properties associated with melanoma progression and the factors involved in Sema5A regulation. ME...

Descripción completa

Detalles Bibliográficos
Autores principales:	D’Aguanno, Simona, Valentini, Elisabetta, Tupone, Maria Grazia, Desideri, Marianna, Di Martile, Marta, Spagnuolo, Manuela, Buglioni, Simonetta, Ercolani, Cristiana, Falcone, Italia, De Dominici, Marco, Milella, Michele, Rizzo, Maria Giulia, Calabretta, Bruno, Cota, Carlo, Anichini, Andrea, Trisciuoglio, Daniela, Del Bufalo, Donatella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245779/ https://www.ncbi.nlm.nih.gov/pubmed/30454024 http://dx.doi.org/10.1186/s13046-018-0933-x

Ejemplares similares

SEMAPHORINS and their receptors: focus on the crosstalk between melanoma and hypoxia
por: Valentini, Elisabetta, et al.
Publicado: (2021)

BCL-X(L) overexpression promotes tumor progression-associated properties
por: Trisciuoglio, Daniela, et al.
Publicado: (2017)

microRNA-378a-5p iS a novel positive regulator of melanoma progression
por: Tupone, Maria Grazia, et al.
Publicado: (2020)

Melanoma-specific bcl-2 promotes a protumoral M2-like phenotype by tumor-associated macrophages
por: Di Martile, Marta, et al.
Publicado: (2020)

Affinity purification-mass spectrometry analysis of bcl-2 interactome identified SLIRP as a novel interacting protein
por: Trisciuoglio, D, et al.
Publicado: (2016)

Inhibition of lysine acetyltransferases impairs tumor angiogenesis acting on both endothelial and tumor cells
por: Di Martile, Marta, et al.
Publicado: (2020)

Histone deacetylase inhibitor ITF2357 leads to apoptosis and enhances doxorubicin cytotoxicity in preclinical models of human sarcoma
por: Di Martile, Marta, et al.
Publicado: (2018)

Antitumor effect of Melaleuca alternifolia essential oil and its main component terpinen-4-ol in combination with target therapy in melanoma models
por: Di Martile, Marta, et al.
Publicado: (2021)

Targeting the anti-apoptotic Bcl-2 family proteins: machine learning virtual screening and biological evaluation of new small molecules
por: Valentini, Elisabetta, et al.
Publicado: (2022)

Inhibition of Anti-Apoptotic Bcl-2 Proteins in Preclinical and Clinical Studies: Current Overview in Cancer
por: D’Aguanno, Simona, et al.
Publicado: (2020)

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells
por: Di Martile, Marta, et al.
Publicado: (2016)

Emerging Role of Histone Acetyltransferase in Stem Cells and Cancer
por: Trisciuoglio, Daniela, et al.
Publicado: (2018)

The multifaceted role of lysine acetylation in cancer: prognostic biomarker and therapeutic target
por: Di Martile, Marta, et al.
Publicado: (2016)

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer
por: Del Bufalo, Donatella, et al.
Publicado: (2014)

Bcl-2-like protein-10 increases aggressive features of melanoma cells
por: Del Bufalo, Donatella, et al.
Publicado: (2022)

Hypoxia-dependent drivers of melanoma progression
por: D’Aguanno, Simona, et al.
Publicado: (2021)

LMNA Knock-Down Affects Differentiation and Progression of Human Neuroblastoma Cells
por: Maresca, Giovanna, et al.
Publicado: (2012)

Special Issue “Precision Oncology in Melanoma Progression”
por: D’Aguanno, Simona
Publicado: (2021)

Editorial: Methods in cancer genetics
por: D’Aguanno, Simona, et al.
Publicado: (2023)

Bcl-2 Regulates HIF-1α Protein Stabilization in Hypoxic Melanoma Cells via the Molecular Chaperone HSP90
por: Trisciuoglio, Daniela, et al.
Publicado: (2010)

Small molecules targeted to the microtubule–Hec1 interaction inhibit cancer cell growth through microtubule stabilization
por: Ferrara, M, et al.
Publicado: (2018)

Effect of cisplatin and c-myb antisense phosphorothioate oligodeoxynucleotides combination on a human colon carcinoma cell line in vitro and in vivo.
por: Del Bufalo, D., et al.
Publicado: (1996)

Multifaceted Functional Role of Semaphorins in Glioblastoma
por: Angelucci, Cristiana, et al.
Publicado: (2019)

Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells
por: Spagnuolo, Manuela, et al.
Publicado: (2019)

Workshop on Colloid Physics : Festschrift Rudolph Klein on the occasion of his 60th birthday
por: Akcasu, A Z, et al.
Publicado: (1995)

Exploring association of melanoma-specific Bcl-xL with tumor immune microenvironment
por: Lucianò, Anna Maria, et al.
Publicado: (2023)

Bcl-2 family inhibitors sensitize human cancer models to therapy
por: Valentini, Elisabetta, et al.
Publicado: (2023)

The semaphorins
por: Yazdani, Umar, et al.
Publicado: (2006)

Vitamin D, a Regulator of Androgen Levels, Is Not Correlated to PSA Serum Levels in a Cohort of the Middle Italy Region Participating to a Prostate Cancer Screening Campaign
por: Crocetto, Felice, et al.
Publicado: (2023)

SEMA6A/RhoA/YAP axis mediates tumor-stroma interactions and prevents response to dual BRAF/MEK inhibition in BRAF-mutant melanoma
por: Loria, Rossella, et al.
Publicado: (2022)

Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition
por: Conciatori, Fabiana, et al.
Publicado: (2022)

Impedance matched thin metamaterials make metals absorbing
por: Mattiucci, N., et al.
Publicado: (2013)

Optimal management of Cogan’s syndrome: a multidisciplinary approach
por: D’Aguanno, Vittorio, et al.
Publicado: (2017)

Thermostatic properties of nitrate molten salts and their solar and eutectic mixtures
por: D’Aguanno, B., et al.
Publicado: (2018)

Successful treatment of acrodermatitis continua of Hallopeau with tildrakizumab: A case report
por: Nguyen, Alex, et al.
Publicado: (2023)

c-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cells
por: Waldron, Todd, et al.
Publicado: (2011)

Essential Oils and Their Main Chemical Components: The Past 20 Years of Preclinical Studies in Melanoma
por: Di Martile, Marta, et al.
Publicado: (2020)

Advances in Tumor-Stroma Interactions: Emerging Role of Cytokine Network in Colorectal and Pancreatic Cancer
por: Bazzichetto, Chiara, et al.
Publicado: (2019)

BRAF status modulates Interelukin-8 expression through a CHOP-dependent mechanism in colorectal cancer
por: Conciatori, Fabiana, et al.
Publicado: (2020)

The thiazole derivative CPTH6 impairs autophagy
por: Ragazzoni, Y, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_1j711c7od12ms5vhp9o1p8jrjd