Sortilin inhibition limits secretion-induced progranulin-dependent breast cancer progression and cancer stem cell expansion

BACKGROUND: Cancer progression is influenced by genetic aberrations in the cancer cell population as well as by other factors including the microenvironment present within a tumour. Direct interactions between various cell types as well as cellular signalling via secreted cytokines can drive key tum...

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Detalles Bibliográficos
Autores principales: Rhost, Sara, Hughes, Éamon, Harrison, Hannah, Rafnsdottir, Svanheidur, Jacobsson, Hanna, Gregersson, Pernilla, Magnusson, Ylva, Fitzpatrick, Paul, Andersson, Daniel, Berger, Karoline, Ståhlberg, Anders, Landberg, Göran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245804/
https://www.ncbi.nlm.nih.gov/pubmed/30454027
http://dx.doi.org/10.1186/s13058-018-1060-5

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