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RAS status and neoadjuvant chemotherapy impact CD8+ cells and tumor HLA class I expression in liver metastatic colorectal cancer

BACKGROUND: T lymphocytes and HLA expression on tumor cell both influence prognostic of localized colorectal cancer, but their role following chemotherapy in patients with liver metastatic colorectal cancer (mCRC) was not addressed. METHODS: One hundred fourteen patients treated in curative intend o...

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Detalles Bibliográficos
Autores principales: Ledys, Fanny, Klopfenstein, Quentin, Truntzer, Caroline, Arnould, Laurent, Vincent, Julie, Bengrine, Leila, Remark, Romain, Boidot, Romain, Ladoire, Sylvain, Ghiringhelli, Francois, Derangere, Valentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245855/
https://www.ncbi.nlm.nih.gov/pubmed/30454021
http://dx.doi.org/10.1186/s40425-018-0438-3