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Matrine attenuates endoplasmic reticulum stress and mitochondrion dysfunction in nonalcoholic fatty liver disease by regulating SERCA pathway

BACKGROUND: Endoplasmic reticulum (ER) stress, which can promote lipid metabolism disorders and steatohepatitis, contributes significantly to the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Calcium (Ca(2+)) homeostasis is considered to play a key role in ER stress. Matrine (Mat) has be...

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Detalles Bibliográficos
Autores principales:	Gao, Xiaobo, Guo, Shun, Zhang, Song, Liu, An, Shi, Lei, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6245862/ https://www.ncbi.nlm.nih.gov/pubmed/30458883 http://dx.doi.org/10.1186/s12967-018-1685-2

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