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Inhibition of GALR1 in PFC Alleviates Depressive-Like Behaviors in Postpartum Depression Rat Model by Upregulating CREB-BNDF and 5-HT Levels

Estrogen (E2) withdrawal is a core pathology mechanism for postpartum depression (PPD). Galanin (GAL), an estrogen-inducible neuropeptide has also been reported to be associated with depression. However, it still remains unclear which GAL receptors (GALRs) are involved in PPD pathologic process. In...

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Detalles Bibliográficos
Autores principales: Li, Hui, Wang, Tong, Shi, Cuige, Yang, Yutao, Li, Xiaoxiao, Wu, Yan, Xu, Zhi-Qing David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246688/
https://www.ncbi.nlm.nih.gov/pubmed/30487761
http://dx.doi.org/10.3389/fpsyt.2018.00588