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SIRT3 Protects Against Acute Kidney Injury via AMPK/mTOR-Regulated Autophagy

Acute kidney injury (AKI), which involves the loss of kidney function caused by damage to renal tubular cells, is an important public health concern. We previously showed that sirtuin (SIRT)3 protects the kidneys against mitochondrial damage by inhibiting the nucleotide-binding domain (NOD)-like rec...

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Detalles Bibliográficos
Autores principales: Zhao, Wenyu, Zhang, Lei, Chen, Rui, Lu, Hanlan, Sui, Mingxing, Zhu, Youhua, Zeng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246697/
https://www.ncbi.nlm.nih.gov/pubmed/30487750
http://dx.doi.org/10.3389/fphys.2018.01526