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Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons

Animals choose among sleep, courtship, and feeding behaviors based on the integration of both external sensory cues and internal states; such choices are essential for survival and reproduction. These competing behaviors are closely related and controlled by distinct neural circuits, but whether the...

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Autores principales: Zhang, Wenxuan, Guo, Chao, Chen, Dandan, Peng, Qionglin, Pan, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246841/
https://www.ncbi.nlm.nih.gov/pubmed/30182322
http://dx.doi.org/10.1007/s12264-018-0281-z
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author Zhang, Wenxuan
Guo, Chao
Chen, Dandan
Peng, Qionglin
Pan, Yufeng
author_facet Zhang, Wenxuan
Guo, Chao
Chen, Dandan
Peng, Qionglin
Pan, Yufeng
author_sort Zhang, Wenxuan
collection PubMed
description Animals choose among sleep, courtship, and feeding behaviors based on the integration of both external sensory cues and internal states; such choices are essential for survival and reproduction. These competing behaviors are closely related and controlled by distinct neural circuits, but whether they are also regulated by shared neural nodes is unclear. Here, we investigated how a set of male-specific P1 neurons controls sleep, courtship, and feeding behaviors in Drosophila males. We found that mild activation of P1 neurons was sufficient to affect sleep, but not courtship or feeding, while stronger activation of P1 neurons labeled by four out of five independent drivers induced courtship, but only the driver that targeted the largest number of P1 neurons affected feeding. These results reveal a common neural node that affects sleep, courtship, and feeding in a threshold-dependent manner, and provide insights into how competing behaviors can be regulated by a shared neural node. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12264-018-0281-z) contains supplementary material, which is available to authorized users.
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spelling pubmed-62468412018-12-04 Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons Zhang, Wenxuan Guo, Chao Chen, Dandan Peng, Qionglin Pan, Yufeng Neurosci Bull Report Animals choose among sleep, courtship, and feeding behaviors based on the integration of both external sensory cues and internal states; such choices are essential for survival and reproduction. These competing behaviors are closely related and controlled by distinct neural circuits, but whether they are also regulated by shared neural nodes is unclear. Here, we investigated how a set of male-specific P1 neurons controls sleep, courtship, and feeding behaviors in Drosophila males. We found that mild activation of P1 neurons was sufficient to affect sleep, but not courtship or feeding, while stronger activation of P1 neurons labeled by four out of five independent drivers induced courtship, but only the driver that targeted the largest number of P1 neurons affected feeding. These results reveal a common neural node that affects sleep, courtship, and feeding in a threshold-dependent manner, and provide insights into how competing behaviors can be regulated by a shared neural node. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s12264-018-0281-z) contains supplementary material, which is available to authorized users. Springer Singapore 2018-09-04 /pmc/articles/PMC6246841/ /pubmed/30182322 http://dx.doi.org/10.1007/s12264-018-0281-z Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Report
Zhang, Wenxuan
Guo, Chao
Chen, Dandan
Peng, Qionglin
Pan, Yufeng
Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons
title Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons
title_full Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons
title_fullStr Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons
title_full_unstemmed Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons
title_short Hierarchical Control of Drosophila Sleep, Courtship, and Feeding Behaviors by Male-Specific P1 Neurons
title_sort hierarchical control of drosophila sleep, courtship, and feeding behaviors by male-specific p1 neurons
topic Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246841/
https://www.ncbi.nlm.nih.gov/pubmed/30182322
http://dx.doi.org/10.1007/s12264-018-0281-z
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