Cargando…

The anti‐metastatic effect of ginsenoside Rb2 in colorectal cancer in an EGFR/SOX2‐dependent manner

Ginsenoside Rb2, a saponin from Panax ginseng, has been shown to have many functions. However, the effect of ginsenoside Rb2 on the metastasis of colorectal cancer (CRC) remains unknown. CRC cell lines HT29 and SW620 were used to determine the effects of ginsenoside Rb2 on the colony‐forming, migrat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phi, Lan Thi Hanh, Wijaya, Yoseph Toni, Sari, Ita Novita, Yang, Ying‐Gui, Lee, Yun Kyung, Kwon, Hyog Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246932/ https://www.ncbi.nlm.nih.gov/pubmed/30264477 http://dx.doi.org/10.1002/cam4.1800

Ejemplares similares

Interferon‐induced transmembrane protein 1‐mediated EGFR/SOX2 signaling axis is essential for progression of non‐small cell lung cancer
por: Yang, Ying‐Gui, et al.
Publicado: (2018)

20(R)-Ginsenoside Rg3 Influences Cancer Stem Cell Properties and the Epithelial-Mesenchymal Transition in Colorectal Cancer via the SNAIL Signaling Axis
por: Phi, Lan Thi Hanh, et al.
Publicado: (2019)

Hedgehog Signaling in Cancer: A Prospective Therapeutic Target for Eradicating Cancer Stem Cells
por: Sari, Ita Novita, et al.
Publicado: (2018)

Amelioration of muscle wasting by gintonin in cancer cachexia
por: Wijaya, Yoseph Toni, et al.
Publicado: (2021)

Ginsenoside Rd ameliorates muscle wasting by suppressing the signal transducer and activator of transcription 3 pathway
por: Wijaya, Yoseph Toni, et al.
Publicado: (2022)

Interferon-induced transmembrane protein 1 (IFITM1) is required for the progression of colorectal cancer
por: Sari, Novita Ita, et al.
Publicado: (2016)

miR551b Regulates Colorectal Cancer Progression by Targeting the ZEB1 Signaling Axis
por: Kim, Kwang Seock, et al.
Publicado: (2019)

Cancer cachexia: molecular mechanisms and treatment strategies
por: Setiawan, Tania, et al.
Publicado: (2023)

Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment
por: Phi, Lan Thi Hanh, et al.
Publicado: (2018)

Toll-Like Receptor 2-Mediated Suppression of Colorectal Cancer Pathogenesis by Polysaccharide A From Bacteroides fragilis
por: Sittipo, Panida, et al.
Publicado: (2018)

EGFR enhances the stemness and progression of oral cancer through inhibiting autophagic degradation of SOX2
por: Lv, Xiao‐Xi, et al.
Publicado: (2019)

Ginsenoside Rb2: A review of pharmacokinetics and pharmacological effects
por: Miao, Longxing, et al.
Publicado: (2022)

ANGPTL1, Foxo3a-Sox2, and colorectal cancer metastasis
por: Jiang, Kai, et al.
Publicado: (2022)

20(S)-ginsenoside Rh2 as agent for the treatment of LMN-CRC via regulating epithelial–mesenchymal transition
por: Yuan, Yihang, et al.
Publicado: (2020)

Ginsenoside Rb2 improves insulin resistance by inhibiting adipocyte pyroptosis
por: Lin, Yi, et al.
Publicado: (2020)

Myostain is involved in ginsenoside Rb1-mediated anti-obesity
por: Li, Hong-Shi, et al.
Publicado: (2022)

Effects of Ginsenoside Rb(1) on Skin Changes
por: Kimura, Yoshiyuki, et al.
Publicado: (2012)

Progress in the Conversion of Ginsenoside Rb1 into Minor Ginsenosides Using β-Glucosidases
por: Zhu, Hongrong, et al.
Publicado: (2023)

Biotransformation of Ginsenoside Rb(1) to Prosapogenins, Gypenoside XVII, Ginsenoside Rd, Ginsenoside F(2), and Compound K by Leuconostoc mesenteroides DC102
por: Quan, Lin-Hu, et al.
Publicado: (2011)

Switches of SOX17 and SOX2 expression in the development of squamous metaplasia and squamous intraepithelial lesions of the uterine cervix
por: Moshi, Jobran M., et al.
Publicado: (2020)

Phosphorylation of pRb: mechanism for RB pathway inactivation in MYCN‐amplified retinoblastoma
por: Ewens, Kathryn G., et al.
Publicado: (2017)

Inhibitory Effects of Ginsenoside-Rb2 on Nicotinic Stimulation-Evoked Catecholamine Secretion
por: Lim, Hyo-Jeong, et al.
Publicado: (2014)

Immunomodulatory Effect of Ginsenoside Rb2 Against Cyclophosphamide-Induced Immunosuppression in Mice
por: Zheng, Siwen, et al.
Publicado: (2022)

Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling–mediated muscular hypertrophy and myoblast differentiation
por: Go, Ga-Yeon, et al.
Publicado: (2020)

Combination of the ginsenosides Rb3 and Rb2 exerts protective effects against myocardial ischemia reperfusion injury in rats
por: Liu, Xiaomin, et al.
Publicado: (2020)

Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats
por: Xiong, Ye, et al.
Publicado: (2010)

Study on the Effect of Ginsenosides Rb on Blood of Tumor Mice
por: Zheng, Mengmeng, et al.
Publicado: (2019)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Biotransformation of ginsenosides Rb(1), Rg(3 )and Rh(2 )in rat gastrointestinal tracts
por: Qian, Tianxiu, et al.
Publicado: (2010)

Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy
por: Yang, Kyeong Eun, et al.
Publicado: (2023)

Enzymatic Biotransformation of Ginsenoside Rb1 and Gypenoside XVII into Ginsenosides Rd and F2 by Recombinant β-glucosidase from Flavobacterium johnsoniae
por: Hong, Hao, et al.
Publicado: (2012)

Translational potential of ginsenoside Rb1 in managing progression of osteoarthritis
por: Chen, Yuanfeng, et al.
Publicado: (2016)

Comprehensive multiomics analysis of the effect of ginsenoside Rb1 on hyperlipidemia
por: Lianqun, Jia, et al.
Publicado: (2021)

Synthesis of ginsenoside Rb(1)-imprinted magnetic polymer nanoparticles for the extraction and cellular delivery of therapeutic ginsenosides
por: Liu, Kai-Hsi, et al.
Publicado: (2022)

Antiviral Effect of Ginsenoside Rb2 and Rb3 Against Bovine Viral Diarrhea Virus and Classical Swine Fever Virus in vitro
por: Tan, Bin, et al.
Publicado: (2021)

LncRNA Sox2ot modulates the progression of thoracic aortic aneurysm by regulating miR-330-5p/Myh11
por: Xiao, Weizhang, et al.
Publicado: (2020)

ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer
por: Chang, Ting-Yu, et al.
Publicado: (2022)

Ginsenoside Rb1 enhances atherosclerotic plaque stability by skewing macrophages to the M2 phenotype
por: Zhang, Xue, et al.
Publicado: (2017)

Ginsenoside Rb2 Alleviates Obesity by Activation of Brown Fat and Induction of Browning of White Fat
por: Hong, Yilian, et al.
Publicado: (2019)

NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma
por: Xiao, Zhi-Jie, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_0i2cappudepf6jvv5lnm9qsdj9