Cargando…

Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial‐mesenchymal transition via Hedgehog signaling pathway

BACKGROUND: Based on previous findings, we hypothesized that Vasohibin 2 (VASH2) protein may induce epithelial‐mesenchymal transition (EMT) of pancreatic cancer (PC) cells by promoting the malignant behaviors of these cells. The present study aimed to test this hypothesis and explore the possible me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ye, Xue, Xiaofeng, Zhao, Xiaoqian, Qin, Lei, Shen, Yu, Dou, Huiqiang, Sun, Jialin, Wang, Tong, Yang, Da‐Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246956/ https://www.ncbi.nlm.nih.gov/pubmed/30318866 http://dx.doi.org/10.1002/cam4.1752

Ejemplares similares

MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
por: Xue, Xiaofeng, et al.
Publicado: (2014)

Hedgehog signaling activation required for glypican-6-mediated regulation of invasion, migration, and epithelial–mesenchymal transition of gastric cancer cells
por: Zeng, Chen, et al.
Publicado: (2020)

HOXD9 promote epithelial‐mesenchymal transition and metastasis in colorectal carcinoma
por: Liu, Mengwei, et al.
Publicado: (2020)

KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition
por: Rao, Chaitra, et al.
Publicado: (2021)

Epithelial–mesenchymal transition, proliferation, and angiogenesis in locally advanced cervical cancer treated with chemoradiotherapy
por: Rojas‐Puentes, Leonardo, et al.
Publicado: (2016)

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer
por: Sun, Jing, et al.
Publicado: (2017)

Chemoradiation induces epithelial‐to‐mesenchymal transition in esophageal adenocarcinoma
por: Steins, Anne, et al.
Publicado: (2019)

LGR5 promotes epithelial ovarian cancer proliferation, metastasis, and epithelial–mesenchymal transition through the Notch1 signaling pathway
por: Liu, Wenxue, et al.
Publicado: (2018)

DACH1 suppresses epithelial to mesenchymal transition (EMT) through Notch1 pathway and reverses progestin resistance in endometrial carcinoma
por: Zhou, Qing, et al.
Publicado: (2019)

CTHRC1 overexpression predicts poor survival and enhances epithelial‐mesenchymal transition in colorectal cancer
por: Ni, Shujuan, et al.
Publicado: (2018)

Epithelial–mesenchymal transition and its transcription factors
por: Debnath, Pallabi, et al.
Publicado: (2021)

Downregulation of NDR1 contributes to metastasis of prostate cancer cells via activating epithelial‐mesenchymal transition
por: Yue, Juntao, et al.
Publicado: (2018)

Fatty acid‐binding protein 5 function in hepatocellular carcinoma through induction of epithelial–mesenchymal transition
por: Ohata, Takanori, et al.
Publicado: (2017)

BACH1 promotes the progression of esophageal squamous cell carcinoma by inducing the epithelial–mesenchymal transition and angiogenesis
por: Zhao, Yan, et al.
Publicado: (2021)

NOTCH3 limits the epithelial–mesenchymal transition and predicts a favorable clinical outcome in esophageal cancer
por: Matsuura, Norihiro, et al.
Publicado: (2021)

Treatment with the vascular disruptive agent OXi4503 induces an immediate and widespread epithelial to mesenchymal transition in the surviving tumor
por: Fifis, Theodora, et al.
Publicado: (2013)

CD44v9 is associated with epithelial‐mesenchymal transition and poor outcomes in esophageal squamous cell carcinoma
por: Taniguchi, Daisuke, et al.
Publicado: (2018)

Long non‐coding RNA HULC stimulates the epithelial–mesenchymal transition process and vasculogenic mimicry in human glioblastoma
por: Yin, Tiantian, et al.
Publicado: (2021)

Dermal fibroblasts induce cell cycle arrest and block epithelial–mesenchymal transition to inhibit the early stage melanoma development
por: Zhou, Linli, et al.
Publicado: (2016)

The role and molecular mechanism of Trop2 induced epithelial‐mesenchymal transition through mediated β‐catenin in gastric cancer
por: Zhao, Wei, et al.
Publicado: (2019)

Activation of hedgehog signaling in mesenchymal stem cells induces cartilage and bone tumor formation via Wnt/β-Catenin
por: Deng, Qi, et al.
Publicado: (2019)

Dihydroartemisinin induces apoptosis and inhibits proliferation, migration, and invasion in epithelial ovarian cancer via inhibition of the hedgehog signaling pathway
por: Liu, Yanmei, et al.
Publicado: (2018)

Vasohibin‐2 is required for epithelial–mesenchymal transition of ovarian cancer cells by modulating transforming growth factor‐β signaling
por: Norita, Rie, et al.
Publicado: (2017)

Overexpression of Snail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cells
por: Fan, Fan, et al.
Publicado: (2012)

Transcriptome profiling reveals novel gene expression signatures and regulating transcription factors of TGF β‐induced epithelial‐to‐mesenchymal transition
por: Du, Liutao, et al.
Publicado: (2016)

MCCK1 enhances the anticancer effect of temozolomide in attenuating the invasion, migration and epithelial‐mesenchymal transition of glioblastoma cells in vitro and in vivo
por: Liu, Tie, et al.
Publicado: (2019)

SMG‐1 inhibition by miR‐192/‐215 causes epithelial‐mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling
por: Zhang, Xiaojing, et al.
Publicado: (2017)

Resveratrol promotes sensitization to Doxorubicin by inhibiting epithelial‐mesenchymal transition and modulating SIRT1/β‐catenin signaling pathway in breast cancer
por: Jin, Xiaoxia, et al.
Publicado: (2019)

Nitidine chloride suppresses epithelial‐mesenchymal transition and stem cell‐like properties in glioblastoma by regulating JAK2/STAT3 signaling
por: Jia, Mingbo, et al.
Publicado: (2021)

Hedgehog Signaling Regulates Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem-Like Cells
por: Wang, Feng, et al.
Publicado: (2016)

The Vasohibin Family
por: Sato, Yasufumi
Publicado: (2010)

Prognostic value of association of OCT4 with LEF1 expression in esophageal squamous cell carcinoma and their impact on epithelial‐mesenchymal transition, invasion, and migration
por: Zhao, Yue, et al.
Publicado: (2018)

CCR7 mediates human breast cancer cell invasion, migration by inducing epithelial–mesenchymal transition and suppressing apoptosis through AKT pathway
por: Xu, Bing, et al.
Publicado: (2017)

LncRNA SNHG12 contributes proliferation, invasion and epithelial–mesenchymal transition of pancreatic cancer cells by absorbing miRNA-320b
por: Cao, Wei, et al.
Publicado: (2020)

Vasohibin-1 suppresses colon cancer
por: Liu, Shuai, et al.
Publicado: (2015)

miR‐130a‐3p regulated TGF‐β1‐induced epithelial‐mesenchymal transition depends on SMAD4 in EC‐1 cells
por: Tian, Xiaokang, et al.
Publicado: (2019)

Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β
por: Mele, Valentina, et al.
Publicado: (2014)

Epithelial‐mesenchymal transition‐converted tumor cells can induce T‐cell apoptosis through upregulation of programmed death ligand 1 expression in esophageal squamous cell carcinoma
por: Thar Min, Aung Kyi, et al.
Publicado: (2018)

The Sonic Hedgehog signaling pathway regulates autophagy and migration in ovarian cancer
por: Pan, Yibin, et al.
Publicado: (2021)

Long intergenic noncoding RNA smad7 (Linc‐smad7) promotes the epithelial‐mesenchymal transition of HCC by targeting the miR‑125b/SIRT6 axis
por: Han, Lili, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_inf9h6bjm1mecd9minv3n73ndj