Cargando…

Lesion Sensing during Initial Binding by Yeast XPC/Rad4: Toward Predicting Resistance to Nucleotide Excision Repair

[Image: see text] Nucleotide excision repair (NER) excises a variety of environmentally derived DNA lesions. However, NER efficiencies for structurally different DNA lesions can vary by orders of magnitude; yet the origin of this variance is poorly understood. Our goal is to develop computational st...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mu, Hong, Zhang, Yingkai, Geacintov, Nicholas E., Broyde, Suse
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2018
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247245/ https://www.ncbi.nlm.nih.gov/pubmed/30284444 http://dx.doi.org/10.1021/acs.chemrestox.8b00231

Ejemplares similares

Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway
por: Mu, Hong, et al.
Publicado: (2017)

Recognition of Damaged DNA for Nucleotide Excision Repair: A Correlated Motion Mechanism with a Mismatched cis-syn Thymine Dimer Lesion
por: Mu, Hong, et al.
Publicado: (2015)

Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair
por: Fu, Iwen, et al.
Publicado: (2022)

Structure and mechanism of pyrimidine–pyrimidone (6-4) photoproduct recognition by the Rad4/XPC nucleotide excision repair complex
por: Paul, Debamita, et al.
Publicado: (2019)

Base Sequence Context Effects on Nucleotide Excision Repair
por: Cai, Yuqin, et al.
Publicado: (2010)

Repair-Resistant DNA Lesions
por: Geacintov, Nicholas E., et al.
Publicado: (2017)

Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies
por: Mu, Hong, et al.
Publicado: (2012)

Light-induced modulation of DNA recognition by the Rad4/XPC damage sensor protein
por: Tavakoli, Amirrasoul, et al.
Publicado: (2021)

Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion–base stacking interactions
por: Reeves, Dara A., et al.
Publicado: (2011)

Structural basis for the recognition of diastereomeric 5′,8-cyclo-2′-deoxypurine lesions by the human nucleotide excision repair system
por: Kropachev, Konstantin, et al.
Publicado: (2014)

Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function
por: Liu, Zhi, et al.
Publicado: (2015)

Entrapment of a Histone Tail by a DNA Lesion in a Nucleosome Suggests the Lesion Impacts Epigenetic Marking: A Molecular Dynamics Study
por: Fu, Iwen, et al.
Publicado: (2015)

Correction: Resistance to Nucleotide Excision Repair of Bulky Guanine Adducts Opposite Abasic Sites in DNA Duplexes and Relationships between Structure and Function
por: Liu, Zhi, et al.
Publicado: (2015)

Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex
por: Chakraborty, Sagnik, et al.
Publicado: (2018)

Structural and Dynamic Characterization of Polymerase κ’s Minor Groove Lesion Processing Reveals How Adduct Topology Impacts Fidelity
por: Lior-Hoffmann, Lee, et al.
Publicado: (2014)

SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair
por: van Cuijk, Loes, et al.
Publicado: (2015)

Tethering-facilitated DNA ‘opening’ and complementary roles of β-hairpin motifs in the Rad4/XPC DNA damage sensor protein
por: Paul, Debamita, et al.
Publicado: (2020)

Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein
por: Kusakabe, Masayuki, et al.
Publicado: (2022)

Structural, energetic and dynamic properties of guanine(C8)–thymine(N3) cross-links in DNA provide insights on susceptibility to nucleotide excision repair
por: Ding, Shuang, et al.
Publicado: (2012)

Preferred WMSA catalytic mechanism of the nucleotidyl transfer reaction in human DNA polymerase κ elucidates error-free bypass of a bulky DNA lesion
por: Lior-Hoffmann, Lee, et al.
Publicado: (2012)

Nucleotide excision repair in Human cell lines lacking both XPC and CSB proteins
por: Lindsey-Boltz, Laura A, et al.
Publicado: (2023)

The N-clasp of human DNA polymerase κ promotes blockage or error-free bypass of adenine- or guanine-benzo[a]pyrenyl lesions
por: Jia, Lei, et al.
Publicado: (2008)

Recognition of DNA damage by XPC coincides with disruption of the XPC–RAD23 complex
por: Bergink, Steven, et al.
Publicado: (2012)

Nucleotide excision repair–initiating proteins bind to oxidative DNA lesions in vivo
por: Menoni, Hervé, et al.
Publicado: (2012)

Nucleotide Excision Repair Factor XPC Ameliorates Prognosis by Increasing the Susceptibility of Human Colorectal Cancer to Chemotherapy and Ionizing Radiation
por: Hu, Liang-Bo, et al.
Publicado: (2018)

Polynuclear ruthenium organometallic compounds induce DNA damage in human cells identified by the nucleotide excision repair factor XPC
por: Fast, Olivia G., et al.
Publicado: (2019)

Excision of Oxidatively Generated Guanine Lesions by Competitive DNA Repair Pathways
por: Shafirovich, Vladimir, et al.
Publicado: (2021)

Mechanism of error-free and semi-targeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4
por: Rechkoblit, Olga, et al.
Publicado: (2010)

Influence of local sequence context on damaged base conformation in human DNA polymerase ι: molecular dynamics studies of nucleotide incorporation opposite a benzo[a]pyrene-derived adenine lesion
por: Donny-Clark, Kerry, et al.
Publicado: (2009)

Nucleotide excision repair of abasic DNA lesions
por: Kitsera, Nataliya, et al.
Publicado: (2019)

Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
por: Rechkoblit, Olga, et al.
Publicado: (2006)

Cryo-EM structure of TFIIH/Rad4–Rad23–Rad33 in damaged DNA opening in nucleotide excision repair
por: van Eeuwen, Trevor, et al.
Publicado: (2021)

Sequence specificity, energetics and mechanism of mismatch recognition by DNA damage sensing protein Rad4/XPC
por: Panigrahi, Abhinandan, et al.
Publicado: (2020)

Treatment of Human HeLa Cells with Black Raspberry Extracts Enhances the Removal of DNA Lesions by the Nucleotide Excision Repair Mechanism
por: Sales, Ana H., et al.
Publicado: (2022)

Nucleotide Excision Repair Protein Rad23 Regulates Cell Virulence Independent of Rad4 in Candida albicans
por: Feng, Jia, et al.
Publicado: (2020)

Following an environmental carcinogen N(2)-dG adduct through replication: elucidating blockage and bypass in a high-fidelity DNA polymerase
por: Xu, Pingna, et al.
Publicado: (2007)

Effects of 5′,8′-Cyclo-2′-Deoxypurines on the Base Excision Repair of Clustered DNA Lesions in Nuclear Extracts of the XPC Cell Line
por: Kaźmierczak-Barańska, Julia, et al.
Publicado: (2021)

Nucleotide Excision Repair and Transcription-coupled DNA Repair Abrogate the Impact of DNA Damage on Transcription
por: Nadkarni, Aditi, et al.
Publicado: (2016)

Nucleotide Excision Repair in Cellular Chromatin: Studies with Yeast from Nucleotide to Gene to Genome
por: Waters, Raymond, et al.
Publicado: (2012)

Kinetic gating mechanism of DNA damage recognition by Rad4/XPC
por: Chen, Xuejing, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_po28e95bmeoiai7hhlhehs3buj