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Parenteral Succinate Reduces Systemic ROS Production in Septic Rats, but It Does Not Reduce Creatinine Levels

In sepsis, reactive oxygen species (ROS) production is increased. This process takes place mainly within the electron transport chain. ROS production is part of the pathophysiology of multiple organ failure in sepsis. Succinate yields Dihydroflavine-Adenine Dinucleotide (FADH(2)), which enters the c...

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Detalles Bibliográficos
Autores principales:	Chapela, Sebastián P., Burgos, Isabel, Congost, Christian, Canzonieri, Romina, Muryan, Alexis, Alonso, Manuel, Stella, Carlos A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247384/ https://www.ncbi.nlm.nih.gov/pubmed/30524651 http://dx.doi.org/10.1155/2018/1928945

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