A Novel Small Peptide Inhibitor of NFκB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer

BACKGROUND: The RH domain of GRK5 is an effective modulator of cancer growth through the inhibition of NFκB activity. The aim of this study was to identify the minimum effective sequence of RH that is still able to inhibit tumor growth and could be used as a peptide-based drug for therapy. METHODS:...

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Detalles Bibliográficos
Autores principales: Gambardella, Jessica, Ciccarelli, Michele, Del Giudice, Carmine, Fiordelisi, Antonella, De Rosa, Matteo, Sala, Marina, Pacelli, Roberto, Campiglia, Pietro, Trimarco, Bruno, Iaccarino, Guido, Sorriento, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247396/
https://www.ncbi.nlm.nih.gov/pubmed/30524659
http://dx.doi.org/10.1155/2018/5801807

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