Data on a rat infection model to assess porous titanium implant coatings

A model is needed to study the effectiveness of different anti-bacterial coatings on complex metal implants in a bone environment. This article shares data on the design of porous titanium implants for intramedullary implantation in the proximal rat tibia. The implant length, diameter and porosity w...

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Detalles Bibliográficos
Autores principales: Croes, M., de Visser, H., Meij, B.P., Lietart, K., van der Wal, B.C.H., Vogely, H.C., Fluit, A.C., Boel, C.H.E., Alblas, J., Weinans, H., Amin Yavari, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Biochemistry, Genetics and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247446/
https://www.ncbi.nlm.nih.gov/pubmed/30505893
http://dx.doi.org/10.1016/j.dib.2018.10.157
Descripción
Sumario:A model is needed to study the effectiveness of different anti-bacterial coatings on complex metal implants in a bone environment. This article shares data on the design of porous titanium implants for intramedullary implantation in the proximal rat tibia. The implant length, diameter and porosity were optimized after testing on cadaveric specimens. This article shares data on which parameters are critical to establish a chronic implant infection in Sprague Dawley rats when using the new implant design. To this end, different strains of Staphylococcus aureus and inoculation doses were investigated.

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