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Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges

BACKGROUND: Various actions have been taken during the last decade to increase the number of organs from deceased donors available for transplantation in Switzerland. This study provides an overview on key figures of the Swiss deceased organ donation and transplant activity between 2008 and 2017. In...

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Autores principales: Weiss, Julius, Elmer, Andreas, Béchir, Markus, Brunner, Christian, Eckert, Philippe, Endermann, Susann, Lenherr, Renato, Nebiker, Mathias, Tisljar, Kai, Haberthür, Christoph, Immer, Franz F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247533/
https://www.ncbi.nlm.nih.gov/pubmed/30458762
http://dx.doi.org/10.1186/s12913-018-3691-8
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author Weiss, Julius
Elmer, Andreas
Béchir, Markus
Brunner, Christian
Eckert, Philippe
Endermann, Susann
Lenherr, Renato
Nebiker, Mathias
Tisljar, Kai
Haberthür, Christoph
Immer, Franz F.
author_facet Weiss, Julius
Elmer, Andreas
Béchir, Markus
Brunner, Christian
Eckert, Philippe
Endermann, Susann
Lenherr, Renato
Nebiker, Mathias
Tisljar, Kai
Haberthür, Christoph
Immer, Franz F.
author_sort Weiss, Julius
collection PubMed
description BACKGROUND: Various actions have been taken during the last decade to increase the number of organs from deceased donors available for transplantation in Switzerland. This study provides an overview on key figures of the Swiss deceased organ donation and transplant activity between 2008 and 2017. In addition, it puts the evolution of the Swiss donation program’s efficiency in relation to the situation in the neighboring countries. METHODS: This study is an analysis of prospective registry data, covering the period from 1 January 2008 to 31 December 2017. It includes all actual deceased organ donors (ADD) in Switzerland. Donor data were extracted from the Swiss Organ Allocation System. The “donor conversion index” (DCI) methodology and data was used for the comparison of donation program efficiency in Switzerland, Germany, Austria, Italy and France. RESULTS: During the study period there were 1116 ADD in Switzerland. The number of ADD per year increased from 91 in 2008 to 145 in 2017 (+ 59%). The reintroduction of the donation after cardiocirculatory death (DCD) program in 2011 resulted in the growth of annual percentages of DCD donors, reaching a maximum of 27% in 2017. The total number of organs transplanted from ADD was 3763 (3.4 ± 1.5 transplants per donor on average). Of these, 48% were kidneys (n = 1814), 24% livers (n = 903), 12% lungs (n = 445), 9% hearts (n = 352) and 7% pancreata or pancreatic islets (n = 249). The donation program efficiency assessment showed an increase of the Swiss DCI from 1.6% in 2008 to 2.7% in 2017 (+ 69%). The most prominent efficiency growth was observed between 2012 and 2017. Even though Swiss donation efficiency increased during the study period, it remained below the DCI of the French and Austrian donation programs. CONCLUSION: Swiss donation activity and efficiency grew during the last decade. The increased donation efficiency suggests that measures implemented so far were effective. The lower efficiency of the Swiss donation program, compared to the French and Austrian programs, may likely be explained by the lower consent rate in Switzerland. This issue should be addressed in order to achieve the goal of more organs available for transplantation.
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spelling pubmed-62475332018-11-26 Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges Weiss, Julius Elmer, Andreas Béchir, Markus Brunner, Christian Eckert, Philippe Endermann, Susann Lenherr, Renato Nebiker, Mathias Tisljar, Kai Haberthür, Christoph Immer, Franz F. BMC Health Serv Res Research Article BACKGROUND: Various actions have been taken during the last decade to increase the number of organs from deceased donors available for transplantation in Switzerland. This study provides an overview on key figures of the Swiss deceased organ donation and transplant activity between 2008 and 2017. In addition, it puts the evolution of the Swiss donation program’s efficiency in relation to the situation in the neighboring countries. METHODS: This study is an analysis of prospective registry data, covering the period from 1 January 2008 to 31 December 2017. It includes all actual deceased organ donors (ADD) in Switzerland. Donor data were extracted from the Swiss Organ Allocation System. The “donor conversion index” (DCI) methodology and data was used for the comparison of donation program efficiency in Switzerland, Germany, Austria, Italy and France. RESULTS: During the study period there were 1116 ADD in Switzerland. The number of ADD per year increased from 91 in 2008 to 145 in 2017 (+ 59%). The reintroduction of the donation after cardiocirculatory death (DCD) program in 2011 resulted in the growth of annual percentages of DCD donors, reaching a maximum of 27% in 2017. The total number of organs transplanted from ADD was 3763 (3.4 ± 1.5 transplants per donor on average). Of these, 48% were kidneys (n = 1814), 24% livers (n = 903), 12% lungs (n = 445), 9% hearts (n = 352) and 7% pancreata or pancreatic islets (n = 249). The donation program efficiency assessment showed an increase of the Swiss DCI from 1.6% in 2008 to 2.7% in 2017 (+ 69%). The most prominent efficiency growth was observed between 2012 and 2017. Even though Swiss donation efficiency increased during the study period, it remained below the DCI of the French and Austrian donation programs. CONCLUSION: Swiss donation activity and efficiency grew during the last decade. The increased donation efficiency suggests that measures implemented so far were effective. The lower efficiency of the Swiss donation program, compared to the French and Austrian programs, may likely be explained by the lower consent rate in Switzerland. This issue should be addressed in order to achieve the goal of more organs available for transplantation. BioMed Central 2018-11-20 /pmc/articles/PMC6247533/ /pubmed/30458762 http://dx.doi.org/10.1186/s12913-018-3691-8 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Weiss, Julius
Elmer, Andreas
Béchir, Markus
Brunner, Christian
Eckert, Philippe
Endermann, Susann
Lenherr, Renato
Nebiker, Mathias
Tisljar, Kai
Haberthür, Christoph
Immer, Franz F.
Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges
title Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges
title_full Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges
title_fullStr Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges
title_full_unstemmed Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges
title_short Deceased organ donation activity and efficiency in Switzerland between 2008 and 2017: achievements and future challenges
title_sort deceased organ donation activity and efficiency in switzerland between 2008 and 2017: achievements and future challenges
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247533/
https://www.ncbi.nlm.nih.gov/pubmed/30458762
http://dx.doi.org/10.1186/s12913-018-3691-8
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