MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease

BACKGROUND: Lung inflammation in COPD is poorly controlled by inhaled corticosteroids (ICS). Strategies to improve ICS efficacy or the search of biomarkers who may select those patients candidates to receive ICS in COPD are needed. Recent data indicate that MUC1 cytoplasmic tail (CT) membrane mucin...

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Detalles Bibliográficos
Autores principales: Milara, Javier, Díaz-Platas, Lucía, Contreras, Sonia, Ribera, Pilar, Roger, Inés, Ballester, Beatriz, Montero, Paula, Cogolludo, Ángel, Morcillo, Esteban, Cortijo, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247701/
https://www.ncbi.nlm.nih.gov/pubmed/30458870
http://dx.doi.org/10.1186/s12931-018-0927-4

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