Cell-free DNA profiling of metastatic prostate cancer reveals microsatellite instability, structural rearrangements and clonal hematopoiesis

BACKGROUND: There are multiple existing and emerging therapeutic avenues for metastatic prostate cancer, with a common denominator, which is the need for predictive biomarkers. Circulating tumor DNA (ctDNA) has the potential to cost-efficiently accelerate precision medicine trials to improve clinica...

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Detalles Bibliográficos
Autores principales: Mayrhofer, Markus, De Laere, Bram, Whitington, Tom, Van Oyen, Peter, Ghysel, Christophe, Ampe, Jozef, Ost, Piet, Demey, Wim, Hoekx, Lucien, Schrijvers, Dirk, Brouwers, Barbara, Lybaert, Willem, Everaert, Els, De Maeseneer, Daan, Strijbos, Michiel, Bols, Alain, Fransis, Karen, Oeyen, Steffi, van Dam, Pieter-Jan, Van den Eynden, Gert, Rutten, Annemie, Aly, Markus, Nordström, Tobias, Van Laere, Steven, Rantalainen, Mattias, Rajan, Prabhakar, Egevad, Lars, Ullén, Anders, Yachnin, Jeffrey, Dirix, Luc, Grönberg, Henrik, Lindberg, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247769/
https://www.ncbi.nlm.nih.gov/pubmed/30458854
http://dx.doi.org/10.1186/s13073-018-0595-5

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