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A central role for P2X7 receptors in human microglia

BACKGROUND: The ATP-gated ionotropic P2X7 receptor (P2X7R) has the unusual ability to function as a small cation channel and a trigger for permeabilization of plasmalemmal membranes. In murine microglia, P2X7R-mediated permeabilization is fundamental to microglial activation, proliferation, and IL-1...

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Detalles Bibliográficos
Autores principales:	Janks, Laura, Sharma, Cristian V. R., Egan, Terrance M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247771/ https://www.ncbi.nlm.nih.gov/pubmed/30463629 http://dx.doi.org/10.1186/s12974-018-1353-8

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