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Nextstrain: real-time tracking of pathogen evolution
SUMMARY: Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive visualization platform. Together these present...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247931/ https://www.ncbi.nlm.nih.gov/pubmed/29790939 http://dx.doi.org/10.1093/bioinformatics/bty407 |
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author | Hadfield, James Megill, Colin Bell, Sidney M Huddleston, John Potter, Barney Callender, Charlton Sagulenko, Pavel Bedford, Trevor Neher, Richard A |
author_facet | Hadfield, James Megill, Colin Bell, Sidney M Huddleston, John Potter, Barney Callender, Charlton Sagulenko, Pavel Bedford, Trevor Neher, Richard A |
author_sort | Hadfield, James |
collection | PubMed |
description | SUMMARY: Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive visualization platform. Together these present a real-time view into the evolution and spread of a range of viral pathogens of high public health importance. The visualization integrates sequence data with other data types such as geographic information, serology, or host species. Nextstrain compiles our current understanding into a single accessible location, open to health professionals, epidemiologists, virologists and the public alike. AVAILABILITY AND IMPLEMENTATION: All code (predominantly JavaScript and Python) is freely available from github.com/nextstrain and the web-application is available at nextstrain.org. |
format | Online Article Text |
id | pubmed-6247931 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-62479312018-11-28 Nextstrain: real-time tracking of pathogen evolution Hadfield, James Megill, Colin Bell, Sidney M Huddleston, John Potter, Barney Callender, Charlton Sagulenko, Pavel Bedford, Trevor Neher, Richard A Bioinformatics Applications Notes SUMMARY: Understanding the spread and evolution of pathogens is important for effective public health measures and surveillance. Nextstrain consists of a database of viral genomes, a bioinformatics pipeline for phylodynamics analysis, and an interactive visualization platform. Together these present a real-time view into the evolution and spread of a range of viral pathogens of high public health importance. The visualization integrates sequence data with other data types such as geographic information, serology, or host species. Nextstrain compiles our current understanding into a single accessible location, open to health professionals, epidemiologists, virologists and the public alike. AVAILABILITY AND IMPLEMENTATION: All code (predominantly JavaScript and Python) is freely available from github.com/nextstrain and the web-application is available at nextstrain.org. Oxford University Press 2018-12-01 2018-05-22 /pmc/articles/PMC6247931/ /pubmed/29790939 http://dx.doi.org/10.1093/bioinformatics/bty407 Text en © The Author(s) 2018. Published by Oxford University Press. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Applications Notes Hadfield, James Megill, Colin Bell, Sidney M Huddleston, John Potter, Barney Callender, Charlton Sagulenko, Pavel Bedford, Trevor Neher, Richard A Nextstrain: real-time tracking of pathogen evolution |
title | Nextstrain: real-time tracking of pathogen evolution |
title_full | Nextstrain: real-time tracking of pathogen evolution |
title_fullStr | Nextstrain: real-time tracking of pathogen evolution |
title_full_unstemmed | Nextstrain: real-time tracking of pathogen evolution |
title_short | Nextstrain: real-time tracking of pathogen evolution |
title_sort | nextstrain: real-time tracking of pathogen evolution |
topic | Applications Notes |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247931/ https://www.ncbi.nlm.nih.gov/pubmed/29790939 http://dx.doi.org/10.1093/bioinformatics/bty407 |
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