Cargando…
The Evolution of Corneal Transplantation
BACKGROUND: The aim of this study was to investigate the evolution of surgical methods in and leading indications for corneal transplantation from 2005 to 2016. MATERIAL/METHODS: Data from the corneal graft waiting list and from all keratoplasties carried out between 2005 and 2016 at the University...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248302/ https://www.ncbi.nlm.nih.gov/pubmed/29242495 http://dx.doi.org/10.12659/AOT.905498 |
_version_ | 1783372616031010816 |
---|---|
author | Röck, Tobias Landenberger, Johanna Bramkamp, Matthias Bartz-Schmidt, Karl Ulrich Röck, Daniel |
author_facet | Röck, Tobias Landenberger, Johanna Bramkamp, Matthias Bartz-Schmidt, Karl Ulrich Röck, Daniel |
author_sort | Röck, Tobias |
collection | PubMed |
description | BACKGROUND: The aim of this study was to investigate the evolution of surgical methods in and leading indications for corneal transplantation from 2005 to 2016. MATERIAL/METHODS: Data from the corneal graft waiting list and from all keratoplasties carried out between 2005 and 2016 at the University Eye Hospital Tübingen were retrospectively evaluated. RESULTS: A total of 1259 keratoplasties were performed between 2005 and 2016 at the University Eye Hospital Tübingen. The most common surgical indications for corneal transplantation were Fuchs endothelial corneal dystrophy (45.5%) and keratoconus (14.2%). The mean rate of corneal transplantations almost doubled from 71 keratoplasties per year in the first 6-year period to 139 keratoplasties per year in the second 6-year period (P=0.005). The number of penetrating keratoplasties remained similar. The number of Descemet membrane endothelial keratoplasties (DMEK) increased significantly from 2008 to 2016 (P<0.0001). One DMEK procedure was performed in 2008 (representing 1.4% of all transplantations), while 75 DMEK procedures were performed in 2016 (representing 60.5% of all transplantations) (P<0.0001). DMEK became the favored surgical method for endothelial disorders, exceeding penetrating keratoplasty in 2013. CONCLUSIONS: Our study shows evolutionary changes in preferred corneal transplantation techniques and leading indications for keratoplasty from 2005 to 2016. Since its introduction a decade ago, DMEK is currently the golden standard in the management of corneal endothelial dysfunction. |
format | Online Article Text |
id | pubmed-6248302 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | International Scientific Literature, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-62483022018-11-28 The Evolution of Corneal Transplantation Röck, Tobias Landenberger, Johanna Bramkamp, Matthias Bartz-Schmidt, Karl Ulrich Röck, Daniel Ann Transplant Original Paper BACKGROUND: The aim of this study was to investigate the evolution of surgical methods in and leading indications for corneal transplantation from 2005 to 2016. MATERIAL/METHODS: Data from the corneal graft waiting list and from all keratoplasties carried out between 2005 and 2016 at the University Eye Hospital Tübingen were retrospectively evaluated. RESULTS: A total of 1259 keratoplasties were performed between 2005 and 2016 at the University Eye Hospital Tübingen. The most common surgical indications for corneal transplantation were Fuchs endothelial corneal dystrophy (45.5%) and keratoconus (14.2%). The mean rate of corneal transplantations almost doubled from 71 keratoplasties per year in the first 6-year period to 139 keratoplasties per year in the second 6-year period (P=0.005). The number of penetrating keratoplasties remained similar. The number of Descemet membrane endothelial keratoplasties (DMEK) increased significantly from 2008 to 2016 (P<0.0001). One DMEK procedure was performed in 2008 (representing 1.4% of all transplantations), while 75 DMEK procedures were performed in 2016 (representing 60.5% of all transplantations) (P<0.0001). DMEK became the favored surgical method for endothelial disorders, exceeding penetrating keratoplasty in 2013. CONCLUSIONS: Our study shows evolutionary changes in preferred corneal transplantation techniques and leading indications for keratoplasty from 2005 to 2016. Since its introduction a decade ago, DMEK is currently the golden standard in the management of corneal endothelial dysfunction. International Scientific Literature, Inc. 2017-12-15 /pmc/articles/PMC6248302/ /pubmed/29242495 http://dx.doi.org/10.12659/AOT.905498 Text en © Ann Transplant, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) ) |
spellingShingle | Original Paper Röck, Tobias Landenberger, Johanna Bramkamp, Matthias Bartz-Schmidt, Karl Ulrich Röck, Daniel The Evolution of Corneal Transplantation |
title | The Evolution of Corneal Transplantation |
title_full | The Evolution of Corneal Transplantation |
title_fullStr | The Evolution of Corneal Transplantation |
title_full_unstemmed | The Evolution of Corneal Transplantation |
title_short | The Evolution of Corneal Transplantation |
title_sort | evolution of corneal transplantation |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248302/ https://www.ncbi.nlm.nih.gov/pubmed/29242495 http://dx.doi.org/10.12659/AOT.905498 |
work_keys_str_mv | AT rocktobias theevolutionofcornealtransplantation AT landenbergerjohanna theevolutionofcornealtransplantation AT bramkampmatthias theevolutionofcornealtransplantation AT bartzschmidtkarlulrich theevolutionofcornealtransplantation AT rockdaniel theevolutionofcornealtransplantation AT rocktobias evolutionofcornealtransplantation AT landenbergerjohanna evolutionofcornealtransplantation AT bramkampmatthias evolutionofcornealtransplantation AT bartzschmidtkarlulrich evolutionofcornealtransplantation AT rockdaniel evolutionofcornealtransplantation |