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Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review

Thromboembolism is a major complication in hospitalized patients. Intensive care unit (ICU) patients have a greater risk of thrombotic events due to additional risk factors such as immobilization, mechanical ventilation, and central catheters. The diagnosis and management of deep vein thrombosis (DV...

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Autores principales: Ejaz, Amna, Ahmed, Munis M, Tasleem, Azka, Rafay Khan Niazi, Muhammad, Ahsraf, Muhammad Farhan, Ahmad, Imama, Zakir, Asma, Raza, Awais
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248708/
https://www.ncbi.nlm.nih.gov/pubmed/30473974
http://dx.doi.org/10.7759/cureus.3341
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author Ejaz, Amna
Ahmed, Munis M
Tasleem, Azka
Rafay Khan Niazi, Muhammad
Ahsraf, Muhammad Farhan
Ahmad, Imama
Zakir, Asma
Raza, Awais
author_facet Ejaz, Amna
Ahmed, Munis M
Tasleem, Azka
Rafay Khan Niazi, Muhammad
Ahsraf, Muhammad Farhan
Ahmad, Imama
Zakir, Asma
Raza, Awais
author_sort Ejaz, Amna
collection PubMed
description Thromboembolism is a major complication in hospitalized patients. Intensive care unit (ICU) patients have a greater risk of thrombotic events due to additional risk factors such as immobilization, mechanical ventilation, and central catheters. The diagnosis and management of deep vein thrombosis (DVT) and pulmonary embolism (PE) in critically ill patients are challenging and these conditions are associated with high mortality. Medical thromboprophylaxis with low molecular weight heparin (LMWH) as well as unfractionated heparin (UFH) has been shown to reduce the incidence of thromboembolic events in such patients. For patients with high risk of bleeding, mechanical thromboprophylaxis can be used. Literature database was conducted on Medline for articles published up to 2018 using particular search terms such as thromboprophylaxis and venous thromboembolism in ICU patients. The following review summarizes the existing data regarding thromboprophylaxis in ICU patients with special consideration to the use of mechanical prophylaxis and pharmacologic prophylaxis using heparin products.
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spelling pubmed-62487082018-11-23 Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review Ejaz, Amna Ahmed, Munis M Tasleem, Azka Rafay Khan Niazi, Muhammad Ahsraf, Muhammad Farhan Ahmad, Imama Zakir, Asma Raza, Awais Cureus Cardiac/Thoracic/Vascular Surgery Thromboembolism is a major complication in hospitalized patients. Intensive care unit (ICU) patients have a greater risk of thrombotic events due to additional risk factors such as immobilization, mechanical ventilation, and central catheters. The diagnosis and management of deep vein thrombosis (DVT) and pulmonary embolism (PE) in critically ill patients are challenging and these conditions are associated with high mortality. Medical thromboprophylaxis with low molecular weight heparin (LMWH) as well as unfractionated heparin (UFH) has been shown to reduce the incidence of thromboembolic events in such patients. For patients with high risk of bleeding, mechanical thromboprophylaxis can be used. Literature database was conducted on Medline for articles published up to 2018 using particular search terms such as thromboprophylaxis and venous thromboembolism in ICU patients. The following review summarizes the existing data regarding thromboprophylaxis in ICU patients with special consideration to the use of mechanical prophylaxis and pharmacologic prophylaxis using heparin products. Cureus 2018-09-21 /pmc/articles/PMC6248708/ /pubmed/30473974 http://dx.doi.org/10.7759/cureus.3341 Text en Copyright © 2018, Ejaz et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiac/Thoracic/Vascular Surgery
Ejaz, Amna
Ahmed, Munis M
Tasleem, Azka
Rafay Khan Niazi, Muhammad
Ahsraf, Muhammad Farhan
Ahmad, Imama
Zakir, Asma
Raza, Awais
Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review
title Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review
title_full Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review
title_fullStr Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review
title_full_unstemmed Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review
title_short Thromboprophylaxis in Intensive Care Unit Patients: A Literature Review
title_sort thromboprophylaxis in intensive care unit patients: a literature review
topic Cardiac/Thoracic/Vascular Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248708/
https://www.ncbi.nlm.nih.gov/pubmed/30473974
http://dx.doi.org/10.7759/cureus.3341
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