The contribution of observational studies in supporting the WHO ‘treat all’ recommendation for HIV/AIDS

In 2015, the World Health Organization (WHO) recommended that all people living with HIV (PLWH) should start antiretroviral therapy (ART) irrespective of clinical or immune status. This recommendation followed almost 20 years of research into the clinical and population-level benefits and risks of s...

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Detalles Bibliográficos
Autores principales: Ford, Nathan, Penazzato, Martina, Vitoria, Marco, Doherty, Meg, Davies, Mary-Ann, Zaniewski, Elizabeth, Tymejczyk, Olga, Egger, Matthias, Nash, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mediscript Ltd 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248853/
https://www.ncbi.nlm.nih.gov/pubmed/30515308
Descripción
Sumario:In 2015, the World Health Organization (WHO) recommended that all people living with HIV (PLWH) should start antiretroviral therapy (ART) irrespective of clinical or immune status. This recommendation followed almost 20 years of research into the clinical and population-level benefits and risks of starting ART early compared with deferring treatment. This article summarises the ways in which observational data support the work of WHO, including the support provided by the International epidemiology Databases to Evaluate AIDS (IeDEA), taking the example of ‘treat all’.

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