Cargando…

EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica

Cutaneous Leishmaniasis (CL) is a parasitic infection classified by the WHO as one of the most uncontrolled spreading neglected diseases. Syria is endemic for Leishmania tropica and Leishmania major, causing CL in the Eastern Mediterranean. The large-scale displacement of Syrian refugees exacerbated...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Hajj, Rana, Bou Youness, Hanady, Lachaud, Laurence, Bastien, Patrick, Masquefa, Carine, Bonnet, Pierre-Antoine, El Hajj, Hiba, Khalifeh, Ibrahim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248897/ https://www.ncbi.nlm.nih.gov/pubmed/30462645 http://dx.doi.org/10.1371/journal.pntd.0006854

Ejemplares similares

EAPB0503, an Imidazoquinoxaline Derivative Modulates SENP3/ARF Mediated SUMOylation, and Induces NPM1c Degradation in NPM1 Mutant AML
por: Skayneh, Hala, et al.
Publicado: (2022)

Lipid nanocapsules formulation and cellular activities evaluation of a promising anticancer agent: EAPB0503
por: Chouchou, Adrien, et al.
Publicado: (2017)

Fatal Visceral Leishmaniasis Caused by Leishmania infantum, Lebanon
por: El Hajj, Rana, et al.
Publicado: (2018)

HAS 1: A natural product from soil-isolated Streptomyces species with potent activity against cutaneous leishmaniasis caused by Leishmania tropica
por: Awada, Bassel, et al.
Publicado: (2022)

Leishmaniasis in Northern Morocco: Predominance of Leishmania infantum Compared to Leishmania tropica
por: Hakkour, Maryam, et al.
Publicado: (2019)

Imiquimod Targets Toxoplasmosis Through Modulating Host Toll-Like Receptor-MyD88 Signaling
por: Hamie, Maguy, et al.
Publicado: (2021)

Efficacy of Systemic Treatment for Leishmania tropica Cutaneous Leishmaniasis
por: SOLOMON, Michal, et al.
Publicado: (2022)

Expanded genome-wide comparisons give novel insights into population structure and genetic heterogeneity of Leishmania tropica complex
por: Salloum, Tamara, et al.
Publicado: (2020)

Drug-Resistant Leishmania tropica Parasites Detected in Iranian Cutaneous Leishmaniasis
Publicado: (2006)

Evolutionary history of Leishmania killicki (synonymous Leishmania tropica) and taxonomic implications
por: Chaara, Dhekra, et al.
Publicado: (2015)

Molecular detection of Leishmania infantum and Leishmania tropica in rodent species from endemic cutaneous leishmaniasis areas in Morocco
por: Echchakery, Mohamed, et al.
Publicado: (2017)

Comparison of Leishmania killicki (syn. L. tropica) and Leishmania tropica Population Structure in Maghreb by Microsatellite Typing
por: Chaara, Dhekra, et al.
Publicado: (2015)

Molecular signatures of anthroponotic cutaneous leishmaniasis in the lesions of patients infected with Leishmania tropica
por: Masoudzadeh, Nasrin, et al.
Publicado: (2020)

Leishmania tropica and Leishmania infantum infection in dogs and cats in central Israel
por: Baneth, Gad, et al.
Publicado: (2022)

Disseminated Leishmaniasis Caused by Leishmania tropica in a Puppy from Karaj, Central Iran
por: Mohebali, M, et al.
Publicado: (2011)

Molecular Evaluation of a Case of Visceral Leishmaniasis Due to Leishmania tropica in Southwestern Iran
por: SARKARI, Bahador, et al.
Publicado: (2016)

Therapeutic Efficacy of Arnica in Hamsters with Cutaneous Leishmaniasis Caused by Leishmania braziliensis and L. tropica
por: Robledo, Sara M., et al.
Publicado: (2022)

Identification of Leishmania tropica from Pediatric Visceral Leishmaniasis in Southern Mediterranean Region of Turkey
por: Alabaz, Derya, et al.
Publicado: (2022)

Domestic dogs carriers of Leishmania infantum, Leishmania tropica and Crithidia fasciculata as potential reservoirs for human visceral leishmaniasis in northeastern Iran
por: Fakhar, Mahdi, et al.
Publicado: (2022)

Detection and molecular typing of Leishmania tropica from Phlebotomus sergenti and lesions of cutaneous leishmaniasis in an emerging focus of Morocco
por: Ajaoud, Malika, et al.
Publicado: (2013)

Leishmania tropica infection in wild and domestic canines
por: Baneth, G, et al.
Publicado: (2014)

Leishmania tropica in Stray Dogs in Southeast Iran
por: BAMOROVAT, Mehdi, et al.
Publicado: (2015)

Inflammatory Nasal Swelling due to Leishmania tropica
por: Fellah, Hajiba, et al.
Publicado: (2021)

Canine leishmaniosis caused by Leishmania major and Leishmania tropica: comparative findings and serology
por: Baneth, Gad, et al.
Publicado: (2017)

Promastigote secretory gel from natural and unnatural sand fly vectors exacerbate Leishmania major and Leishmania tropica cutaneous leishmaniasis in mice
por: Giraud, E., et al.
Publicado: (2019)

Association of Phlebotomus guggisbergi with Leishmania major and Leishmania tropica in a complex transmission setting for cutaneous leishmaniasis in Gilgil, Nakuru county, Kenya
por: Owino, Barrack O., et al.
Publicado: (2019)

Unresponsiveness to Glucantime Treatment in Iranian Cutaneous Leishmaniasis due to Drug-Resistant Leishmania tropica Parasites
por: Hadighi, Ramtin, et al.
Publicado: (2006)

Mucocutaneous Leishmania tropica infection in a dog from a human cutaneous leishmaniasis focus
por: Baneth, Gad, et al.
Publicado: (2014)

Complicated cutaneous leishmaniasis caused by an imported case of Leishmania tropica in Japan: a case report
por: Kitano, Hiroyuki, et al.
Publicado: (2021)

Determinants of Unresponsiveness to Treatment in Cutaneous Leishmaniasis: A Focus on Anthroponotic Form Due to Leishmania tropica
por: Bamorovat, Mehdi, et al.
Publicado: (2021)

The Genetic Relationship between Leishmania aethiopica and Leishmania tropica Revealed by Comparing Microsatellite Profiles
por: Krayter, Lena, et al.
Publicado: (2015)

In Vitro and In Vivo Antileishmanial Effects of Pistacia khinjuk against Leishmania tropica and Leishmania major
por: Ezatpour, Behrouz, et al.
Publicado: (2015)

Predominance of Leishmania major and rare occurrence of Leishmania tropica with haplotype variability at the center of Iran
por: Zahirnia, Amir Hossein, et al.
Publicado: (2018)

Possible introduction of Leishmania tropica to urban areas determined by epidemiological and clinical profiles of patients with cutaneous leishmaniasis in Casablanca (Morocco)
por: Baghad, Bouchra, et al.
Publicado: (2020)

Mapping the Genes for Susceptibility and Response to Leishmania tropica in Mouse
por: Sohrabi, Yahya, et al.
Publicado: (2013)

Chiclero's ulcer: An unusual presentation of Leishmania tropica in Syria
por: Youssef, Alexey, et al.
Publicado: (2018)

Leishmania tropica infection of the ear treated with photodynamic therapy
por: Goldin, Harry, et al.
Publicado: (2020)

Super Infection of Cutaneous Leishmaniasis Caused by Leishmania major and L. tropica to Crithidia fasciculata in Shiraz, Iran
por: MIRZAPOUR, Aliyar, et al.
Publicado: (2019)

Genotypic and phylogenic analyses of cutaneous leishmaniasis in Al Ahsa, Eastern Saudi Arabia during the coronavirus disease 2019 pandemic: First cases of Leishmania tropica with the predominance of Leishmania major
por: Al-Rashed, Abdullatif S., et al.
Publicado: (2022)

Moroccan strains of Leishmania major and Leishmania tropica differentially impact on nitric oxide production by macrophages
por: Maksouri, Hasnaa, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_40kc9kf8udteloua3r6h64i4su