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Cortical control of a tablet computer by people with paralysis

General-purpose computers have become ubiquitous and important for everyday life, but they are difficult for people with paralysis to use. Specialized software and personalized input devices can improve access, but often provide only limited functionality. In this study, three research participants...

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Detalles Bibliográficos
Autores principales: Nuyujukian, Paul, Albites Sanabria, Jose, Saab, Jad, Pandarinath, Chethan, Jarosiewicz, Beata, Blabe, Christine H., Franco, Brian, Mernoff, Stephen T., Eskandar, Emad N., Simeral, John D., Hochberg, Leigh R., Shenoy, Krishna V., Henderson, Jaimie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248919/
https://www.ncbi.nlm.nih.gov/pubmed/30462658
http://dx.doi.org/10.1371/journal.pone.0204566
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author Nuyujukian, Paul
Albites Sanabria, Jose
Saab, Jad
Pandarinath, Chethan
Jarosiewicz, Beata
Blabe, Christine H.
Franco, Brian
Mernoff, Stephen T.
Eskandar, Emad N.
Simeral, John D.
Hochberg, Leigh R.
Shenoy, Krishna V.
Henderson, Jaimie M.
author_facet Nuyujukian, Paul
Albites Sanabria, Jose
Saab, Jad
Pandarinath, Chethan
Jarosiewicz, Beata
Blabe, Christine H.
Franco, Brian
Mernoff, Stephen T.
Eskandar, Emad N.
Simeral, John D.
Hochberg, Leigh R.
Shenoy, Krishna V.
Henderson, Jaimie M.
author_sort Nuyujukian, Paul
collection PubMed
description General-purpose computers have become ubiquitous and important for everyday life, but they are difficult for people with paralysis to use. Specialized software and personalized input devices can improve access, but often provide only limited functionality. In this study, three research participants with tetraplegia who had multielectrode arrays implanted in motor cortex as part of the BrainGate2 clinical trial used an intracortical brain-computer interface (iBCI) to control an unmodified commercial tablet computer. Neural activity was decoded in real time as a point-and-click wireless Bluetooth mouse, allowing participants to use common and recreational applications (web browsing, email, chatting, playing music on a piano application, sending text messages, etc.). Two of the participants also used the iBCI to “chat” with each other in real time. This study demonstrates, for the first time, high-performance iBCI control of an unmodified, commercially available, general-purpose mobile computing device by people with tetraplegia.
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spelling pubmed-62489192018-12-06 Cortical control of a tablet computer by people with paralysis Nuyujukian, Paul Albites Sanabria, Jose Saab, Jad Pandarinath, Chethan Jarosiewicz, Beata Blabe, Christine H. Franco, Brian Mernoff, Stephen T. Eskandar, Emad N. Simeral, John D. Hochberg, Leigh R. Shenoy, Krishna V. Henderson, Jaimie M. PLoS One Research Article General-purpose computers have become ubiquitous and important for everyday life, but they are difficult for people with paralysis to use. Specialized software and personalized input devices can improve access, but often provide only limited functionality. In this study, three research participants with tetraplegia who had multielectrode arrays implanted in motor cortex as part of the BrainGate2 clinical trial used an intracortical brain-computer interface (iBCI) to control an unmodified commercial tablet computer. Neural activity was decoded in real time as a point-and-click wireless Bluetooth mouse, allowing participants to use common and recreational applications (web browsing, email, chatting, playing music on a piano application, sending text messages, etc.). Two of the participants also used the iBCI to “chat” with each other in real time. This study demonstrates, for the first time, high-performance iBCI control of an unmodified, commercially available, general-purpose mobile computing device by people with tetraplegia. Public Library of Science 2018-11-21 /pmc/articles/PMC6248919/ /pubmed/30462658 http://dx.doi.org/10.1371/journal.pone.0204566 Text en https://creativecommons.org/publicdomain/zero/1.0/ This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Nuyujukian, Paul
Albites Sanabria, Jose
Saab, Jad
Pandarinath, Chethan
Jarosiewicz, Beata
Blabe, Christine H.
Franco, Brian
Mernoff, Stephen T.
Eskandar, Emad N.
Simeral, John D.
Hochberg, Leigh R.
Shenoy, Krishna V.
Henderson, Jaimie M.
Cortical control of a tablet computer by people with paralysis
title Cortical control of a tablet computer by people with paralysis
title_full Cortical control of a tablet computer by people with paralysis
title_fullStr Cortical control of a tablet computer by people with paralysis
title_full_unstemmed Cortical control of a tablet computer by people with paralysis
title_short Cortical control of a tablet computer by people with paralysis
title_sort cortical control of a tablet computer by people with paralysis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248919/
https://www.ncbi.nlm.nih.gov/pubmed/30462658
http://dx.doi.org/10.1371/journal.pone.0204566
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