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Neddylation contributes to CD4(+) T cell-mediated protective immunity against blood-stage Plasmodium infection
CD4(+) T cells play predominant roles in protective immunity against blood-stage Plasmodium infection, both for IFN-γ-dependent effector mechanisms and providing B cell helper signals. Neddylation, an ubiquitination-like process triggered by covalent conjugation of NEDD8 to specific targets, has eme...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249024/ https://www.ncbi.nlm.nih.gov/pubmed/30462731 http://dx.doi.org/10.1371/journal.ppat.1007440 |