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The Trans Golgi Region is a Labile Intracellular Ca(2+) Store Sensitive to Emetine

The Golgi apparatus (GA) is a bona fide Ca(2+) store; however, there is a lack of GA-specific Ca(2+) mobilizing agents. Here, we report that emetine specifically releases Ca(2+) from GA in HeLa and HL-1 atrial myocytes. Additionally, it has become evident that the trans-Golgi is a labile Ca(2+) stor...

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Detalles Bibliográficos
Autores principales: Gallegos-Gómez, Martín-Leonardo, Greotti, Elisa, López-Méndez, María-Cristina, Sánchez-Vázquez, Víctor-Hugo, Arias, Juan-Manuel, Guerrero-Hernández, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249204/
https://www.ncbi.nlm.nih.gov/pubmed/30464185
http://dx.doi.org/10.1038/s41598-018-35280-z