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Survival of midbrain dopamine neurons depends on the Bcl2 factor Mcl1
Mitochondria-dependent apoptosis plays an important role in the embryonic development of the midbrain dopaminergic system as well as in Parkinson’s disease. Central to mitochondria-dependent apoptosis is the Bcl2 family of apoptosis-regulating proteins. However, it was unclear which Bcl2 proteins ar...
Autores principales: | Robinson, Edward J., Aguiar, Sebastian P., Kouwenhoven, Willemieke M., Starmans, Dorinde S., von Oerthel, Lars, Smidt, Marten P., van der Heide, Lars P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249233/ https://www.ncbi.nlm.nih.gov/pubmed/30479840 http://dx.doi.org/10.1038/s41420-018-0125-7 |
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