Suppression of Hepatic Bile Acid Synthesis by a non-tumorigenic FGF19 analogue Protects Mice from Fibrosis and Hepatocarcinogenesis

Critical regulation of bile acid (BA) pool size and composition occurs via an intensive molecular crosstalk between the liver and gut, orchestrated by the combined actions of the nuclear Farnesoid X receptor (FXR) and the enterokine fibroblast growth factor 19 (FGF19) with the final aim of reducing...

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Detalles Bibliográficos
Autores principales: Gadaleta, Raffaella Maria, Scialpi, Natasha, Peres, Claudia, Cariello, Marica, Ko, Brian, Luo, Jian, Porru, Emanuele, Roda, Aldo, Sabbà, Carlo, Moschetta, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249240/
https://www.ncbi.nlm.nih.gov/pubmed/30464200
http://dx.doi.org/10.1038/s41598-018-35496-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249240/
https://www.ncbi.nlm.nih.gov/pubmed/30464200
http://dx.doi.org/10.1038/s41598-018-35496-z

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