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Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests
Testing for association between a set of genetic markers and a phenotype is a fundamental task in genetic studies. Standard approaches for heritability and set testing strongly rely on parametric models that make specific assumptions regarding phenotypic variability. Here, we show that resulting p-v...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249264/ https://www.ncbi.nlm.nih.gov/pubmed/30464216 http://dx.doi.org/10.1038/s41467-018-07276-w |