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Highly Selective 5-Formyluracil Labeling and Genome-wide Mapping Using (2-Benzimidazolyl)Acetonitrile Probe

Chemical modifications to nucleobases have a great influence on various cellular processes, by making gene regulation more complex, thus indicating their profound impact on aspects of heredity, growth, and disease. Here, we provide the first genome-wide map of 5-formyluracil (5fU) in living tissues...

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Detalles Bibliográficos
Autores principales: Wang, Yafen, Liu, Chaoxing, Wu, Fan, Zhang, Xiong, Liu, Sheng, Chen, Zonggui, Zeng, Weiwu, Yang, Wei, Zhang, Xiaolian, Zhou, Yu, Weng, Xiaocheng, Wu, Zhiguo, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249349/
https://www.ncbi.nlm.nih.gov/pubmed/30466066
http://dx.doi.org/10.1016/j.isci.2018.10.024