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FMRP Interacts with C/D Box snoRNA in the Nucleus and Regulates Ribosomal RNA Methylation
FMRP is an RNA-binding protein that is known to localize in the cytoplasm and in the nucleus. Here, we have identified an interaction of FMRP with a specific set of C/D box snoRNAs in the nucleus. C/D box snoRNAs guide 2’O methylations of ribosomal RNA (rRNA) on defined sites, and this modification...
Autores principales: | D'Souza, Michelle Ninochka, Gowda, Naveen Kumar Chandappa, Tiwari, Vishal, Babu, Rosana Ottakandathil, Anand, Praveen, Dastidar, Sudhriti Ghosh, Singh, Randhir, Selvaraja, Bhuvaneish, Pal, Rakhi, Ramesh, Arati, Chattarji, Sumantra, Chandran, Siddharthan, Gulyani, Akash, Palakodeti, Dasaradhi, Muddashetty, Ravi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249352/ https://www.ncbi.nlm.nih.gov/pubmed/30469012 http://dx.doi.org/10.1016/j.isci.2018.11.007 |
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