Early Microglial Activation Following Closed-Head Concussive Injury Is Dominated by Pro-Inflammatory M-1 Type

Microglial activation is a pathological hallmark of traumatic brain injury (TBI). Following brain injury, activated microglia/macrophages adopt different phenotypes, generally categorized as M-1, or classically activated, and M-2, or alternatively activated. While the M-1, or pro-inflammatory phenot...

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Detalles Bibliográficos
Autores principales: Madathil, Sindhu K., Wilfred, Bernard S., Urankar, Sarah E., Yang, Weihong, Leung, Lai Yee, Gilsdorf, Janice S., Shear, Deborah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249371/
https://www.ncbi.nlm.nih.gov/pubmed/30498469
http://dx.doi.org/10.3389/fneur.2018.00964

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