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Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle

Prediction of tumor volume using the Cavalieri method may be helpful in management of therapy and evaluation of treatment results. The aim of this study was to adapt the Cavalieri stereological method to magnetic resonance imaging for determining volume of nasopharyngeal cancers and assess changes a...

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Autores principales: Tatar, Arzu, Ozmen, Hilal Kiziltunc, Yoruk, Ozgur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249478/
https://www.ncbi.nlm.nih.gov/pubmed/30255692
http://dx.doi.org/10.22034/APJCP.2018.19.9.2403
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author Tatar, Arzu
Ozmen, Hilal Kiziltunc
Yoruk, Ozgur
author_facet Tatar, Arzu
Ozmen, Hilal Kiziltunc
Yoruk, Ozgur
author_sort Tatar, Arzu
collection PubMed
description Prediction of tumor volume using the Cavalieri method may be helpful in management of therapy and evaluation of treatment results. The aim of this study was to adapt the Cavalieri stereological method to magnetic resonance imaging for determining volume of nasopharyngeal cancers and assess changes after treatment using the Cavalieri method. Serial MRI images in the sagittal plane were obtained from a total of 33 patients with nasopharyngeal carcinomas (11 with stage T2, 11 with stage T3, and 11 with stage T4 lesions). The images were analyzed retrospectively before and two months following the cessation of radiochemotherapy for comparison. Average tumor volumes before and after treatment in patients with stage T2 were 21. 5±10.5 cm3 and 2.82±3.43 cm(3), respectively (p=0.000). The respective figures were 35.1±19.0 cm3 and 6.27±7.82 cm(3) (p=0.000) for stage T3 cases, and 62.8±27.8 cm3 and 11. 6±11.9 cm3 (p=0.000) for stage T4. Post-treatment tumor volumes were statistically reduced when compared to pre-treatment volumes in all stages.
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spelling pubmed-62494782018-12-07 Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle Tatar, Arzu Ozmen, Hilal Kiziltunc Yoruk, Ozgur Asian Pac J Cancer Prev Research Article Prediction of tumor volume using the Cavalieri method may be helpful in management of therapy and evaluation of treatment results. The aim of this study was to adapt the Cavalieri stereological method to magnetic resonance imaging for determining volume of nasopharyngeal cancers and assess changes after treatment using the Cavalieri method. Serial MRI images in the sagittal plane were obtained from a total of 33 patients with nasopharyngeal carcinomas (11 with stage T2, 11 with stage T3, and 11 with stage T4 lesions). The images were analyzed retrospectively before and two months following the cessation of radiochemotherapy for comparison. Average tumor volumes before and after treatment in patients with stage T2 were 21. 5±10.5 cm3 and 2.82±3.43 cm(3), respectively (p=0.000). The respective figures were 35.1±19.0 cm3 and 6.27±7.82 cm(3) (p=0.000) for stage T3 cases, and 62.8±27.8 cm3 and 11. 6±11.9 cm3 (p=0.000) for stage T4. Post-treatment tumor volumes were statistically reduced when compared to pre-treatment volumes in all stages. West Asia Organization for Cancer Prevention 2018 /pmc/articles/PMC6249478/ /pubmed/30255692 http://dx.doi.org/10.22034/APJCP.2018.19.9.2403 Text en Copyright: © Asian Pacific Journal of Cancer Prevention http://creativecommons.org/licenses/BY-SA/4.0 This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
spellingShingle Research Article
Tatar, Arzu
Ozmen, Hilal Kiziltunc
Yoruk, Ozgur
Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle
title Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle
title_full Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle
title_fullStr Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle
title_full_unstemmed Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle
title_short Evaluation of Volume of Nasopharyngeal Cancers by the Cavalieri Principle
title_sort evaluation of volume of nasopharyngeal cancers by the cavalieri principle
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249478/
https://www.ncbi.nlm.nih.gov/pubmed/30255692
http://dx.doi.org/10.22034/APJCP.2018.19.9.2403
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