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Association of C3435T, C1236T and C4125A Polymorphisms of the MDR-1 Gene in Egyptian Children with Acute Lymphoblastic Leukaemia

BACKGROUND: P-glycoprotein (P-gp), a membrane transporter encoded by the multidrug resistance-1 (MDR1) gene, influences pharmacokinetics and metabolism of anticancer drugs and contributes to multidrug resistance phenotype in acute lymphoblastic leukemia (ALL). Genetic variation ofMDR1 in ALL patient...

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Detalles Bibliográficos
Autores principales:	Talaat, Roba M, El-Kelliny, MedhatY K, El-Akhras, Basima A, Bakry, Rania M, Riad, Khaled F, Guirgis, Adel A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249480/ https://www.ncbi.nlm.nih.gov/pubmed/30256048 http://dx.doi.org/10.22034/APJCP.2018.19.9.2535

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