Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO

Nitric oxide (NO) donor drugs have a range of clinical applications, and are also being developed as therapeutics for the potential treatment of multiple diseases. This article presents data describing the synthesis and characterisation of a novel NO releasing nanoparticle formed by encapsulation of...

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Autores principales: Alimoradi, Houman, Barzegar-Fallah, Anita, Sammut, Ivan A., Greish, Khaled, Giles, Gregory I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Pharmacology, Toxicology and Pharmaceutical Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249518/
https://www.ncbi.nlm.nih.gov/pubmed/30505914
http://dx.doi.org/10.1016/j.dib.2018.10.149
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author Alimoradi, Houman
Barzegar-Fallah, Anita
Sammut, Ivan A.
Greish, Khaled
Giles, Gregory I.
author_facet Alimoradi, Houman
Barzegar-Fallah, Anita
Sammut, Ivan A.
Greish, Khaled
Giles, Gregory I.
author_sort Alimoradi, Houman
collection PubMed
description Nitric oxide (NO) donor drugs have a range of clinical applications, and are also being developed as therapeutics for the potential treatment of multiple diseases. This article presents data describing the synthesis and characterisation of a novel NO releasing nanoparticle formed by encapsulation of the NO donor tDodSNO into a co-polymer of styrene and maleic acid (SMA) to afford SMA-tDodSNO. The pharmacological activity of SMA-tDodSNO is discussed in our accompanying manuscript “Encapsulation of tDodSNO generates a photoactivated nitric oxide releasing nanoparticle for localized control of vasodilation and vascular hyperpermeability”. (Alimoradio et al. [1]).
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spelling pubmed-62495182018-11-30 Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO Alimoradi, Houman Barzegar-Fallah, Anita Sammut, Ivan A. Greish, Khaled Giles, Gregory I. Data Brief Pharmacology, Toxicology and Pharmaceutical Science Nitric oxide (NO) donor drugs have a range of clinical applications, and are also being developed as therapeutics for the potential treatment of multiple diseases. This article presents data describing the synthesis and characterisation of a novel NO releasing nanoparticle formed by encapsulation of the NO donor tDodSNO into a co-polymer of styrene and maleic acid (SMA) to afford SMA-tDodSNO. The pharmacological activity of SMA-tDodSNO is discussed in our accompanying manuscript “Encapsulation of tDodSNO generates a photoactivated nitric oxide releasing nanoparticle for localized control of vasodilation and vascular hyperpermeability”. (Alimoradio et al. [1]). Elsevier 2018-11-03 /pmc/articles/PMC6249518/ /pubmed/30505914 http://dx.doi.org/10.1016/j.dib.2018.10.149 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Pharmacology, Toxicology and Pharmaceutical Science
Alimoradi, Houman
Barzegar-Fallah, Anita
Sammut, Ivan A.
Greish, Khaled
Giles, Gregory I.
Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO
title Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO
title_full Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO
title_fullStr Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO
title_full_unstemmed Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO
title_short Data characterizing the biophysical and nitric oxide release properties of the tDodSNO – Styrene maleic anhydride nanoparticle SMA-tDodSNO
title_sort data characterizing the biophysical and nitric oxide release properties of the tdodsno – styrene maleic anhydride nanoparticle sma-tdodsno
topic Pharmacology, Toxicology and Pharmaceutical Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249518/
https://www.ncbi.nlm.nih.gov/pubmed/30505914
http://dx.doi.org/10.1016/j.dib.2018.10.149
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