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Oncological treatment and outcome of colorectal cancer in Greenland

Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and surv...

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Autores principales: Odgaard, Marie, Lohse, Nicolai, Petersen, Alice Juhl, Bæksgaard, Lene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249539/
https://www.ncbi.nlm.nih.gov/pubmed/30458696
http://dx.doi.org/10.1080/22423982.2018.1546069
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author Odgaard, Marie
Lohse, Nicolai
Petersen, Alice Juhl
Bæksgaard, Lene
author_facet Odgaard, Marie
Lohse, Nicolai
Petersen, Alice Juhl
Bæksgaard, Lene
author_sort Odgaard, Marie
collection PubMed
description Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and survival for the first 8 years of treatment. The study was a registry-based observational study of all patients in Greenland diagnosed with histologically verified CRC from August 2004 to August 2012. Analyses were stratified according to stage and discussed in relation to reported data from patients with CRC in Denmark. 180 patients were included. . Stage I, II, III, and IV comprised 15, 34, 23, and 23%, respectively. 5% presented with unknown stage. A total of 51% received oncological treatment. 79% of patients with Stage III disease received adjuvant chemotherapy, 61% of patients with metastatic CRC received palliative chemotherapy. Five-year survival was 48 and 53% for colon and rectum cancer, respectively. An insignificant trend towards higher survival in men than in women was seen; adjusted hazard ratio for death (women vs men) = 1.46 (95% CI = 0.97–2.19). In conclusion; Stage distribution, provision of oncological treatment and 5-year survival were comparable to patients diagnosed and treated in Denmark.
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spelling pubmed-62495392018-11-26 Oncological treatment and outcome of colorectal cancer in Greenland Odgaard, Marie Lohse, Nicolai Petersen, Alice Juhl Bæksgaard, Lene Int J Circumpolar Health Research Article Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and survival for the first 8 years of treatment. The study was a registry-based observational study of all patients in Greenland diagnosed with histologically verified CRC from August 2004 to August 2012. Analyses were stratified according to stage and discussed in relation to reported data from patients with CRC in Denmark. 180 patients were included. . Stage I, II, III, and IV comprised 15, 34, 23, and 23%, respectively. 5% presented with unknown stage. A total of 51% received oncological treatment. 79% of patients with Stage III disease received adjuvant chemotherapy, 61% of patients with metastatic CRC received palliative chemotherapy. Five-year survival was 48 and 53% for colon and rectum cancer, respectively. An insignificant trend towards higher survival in men than in women was seen; adjusted hazard ratio for death (women vs men) = 1.46 (95% CI = 0.97–2.19). In conclusion; Stage distribution, provision of oncological treatment and 5-year survival were comparable to patients diagnosed and treated in Denmark. Taylor & Francis 2018-11-20 /pmc/articles/PMC6249539/ /pubmed/30458696 http://dx.doi.org/10.1080/22423982.2018.1546069 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Odgaard, Marie
Lohse, Nicolai
Petersen, Alice Juhl
Bæksgaard, Lene
Oncological treatment and outcome of colorectal cancer in Greenland
title Oncological treatment and outcome of colorectal cancer in Greenland
title_full Oncological treatment and outcome of colorectal cancer in Greenland
title_fullStr Oncological treatment and outcome of colorectal cancer in Greenland
title_full_unstemmed Oncological treatment and outcome of colorectal cancer in Greenland
title_short Oncological treatment and outcome of colorectal cancer in Greenland
title_sort oncological treatment and outcome of colorectal cancer in greenland
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249539/
https://www.ncbi.nlm.nih.gov/pubmed/30458696
http://dx.doi.org/10.1080/22423982.2018.1546069
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