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Oncological treatment and outcome of colorectal cancer in Greenland
Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and surv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249539/ https://www.ncbi.nlm.nih.gov/pubmed/30458696 http://dx.doi.org/10.1080/22423982.2018.1546069 |
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author | Odgaard, Marie Lohse, Nicolai Petersen, Alice Juhl Bæksgaard, Lene |
author_facet | Odgaard, Marie Lohse, Nicolai Petersen, Alice Juhl Bæksgaard, Lene |
author_sort | Odgaard, Marie |
collection | PubMed |
description | Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and survival for the first 8 years of treatment. The study was a registry-based observational study of all patients in Greenland diagnosed with histologically verified CRC from August 2004 to August 2012. Analyses were stratified according to stage and discussed in relation to reported data from patients with CRC in Denmark. 180 patients were included. . Stage I, II, III, and IV comprised 15, 34, 23, and 23%, respectively. 5% presented with unknown stage. A total of 51% received oncological treatment. 79% of patients with Stage III disease received adjuvant chemotherapy, 61% of patients with metastatic CRC received palliative chemotherapy. Five-year survival was 48 and 53% for colon and rectum cancer, respectively. An insignificant trend towards higher survival in men than in women was seen; adjusted hazard ratio for death (women vs men) = 1.46 (95% CI = 0.97–2.19). In conclusion; Stage distribution, provision of oncological treatment and 5-year survival were comparable to patients diagnosed and treated in Denmark. |
format | Online Article Text |
id | pubmed-6249539 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Taylor & Francis |
record_format | MEDLINE/PubMed |
spelling | pubmed-62495392018-11-26 Oncological treatment and outcome of colorectal cancer in Greenland Odgaard, Marie Lohse, Nicolai Petersen, Alice Juhl Bæksgaard, Lene Int J Circumpolar Health Research Article Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and survival for the first 8 years of treatment. The study was a registry-based observational study of all patients in Greenland diagnosed with histologically verified CRC from August 2004 to August 2012. Analyses were stratified according to stage and discussed in relation to reported data from patients with CRC in Denmark. 180 patients were included. . Stage I, II, III, and IV comprised 15, 34, 23, and 23%, respectively. 5% presented with unknown stage. A total of 51% received oncological treatment. 79% of patients with Stage III disease received adjuvant chemotherapy, 61% of patients with metastatic CRC received palliative chemotherapy. Five-year survival was 48 and 53% for colon and rectum cancer, respectively. An insignificant trend towards higher survival in men than in women was seen; adjusted hazard ratio for death (women vs men) = 1.46 (95% CI = 0.97–2.19). In conclusion; Stage distribution, provision of oncological treatment and 5-year survival were comparable to patients diagnosed and treated in Denmark. Taylor & Francis 2018-11-20 /pmc/articles/PMC6249539/ /pubmed/30458696 http://dx.doi.org/10.1080/22423982.2018.1546069 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Odgaard, Marie Lohse, Nicolai Petersen, Alice Juhl Bæksgaard, Lene Oncological treatment and outcome of colorectal cancer in Greenland |
title | Oncological treatment and outcome of colorectal cancer in Greenland |
title_full | Oncological treatment and outcome of colorectal cancer in Greenland |
title_fullStr | Oncological treatment and outcome of colorectal cancer in Greenland |
title_full_unstemmed | Oncological treatment and outcome of colorectal cancer in Greenland |
title_short | Oncological treatment and outcome of colorectal cancer in Greenland |
title_sort | oncological treatment and outcome of colorectal cancer in greenland |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249539/ https://www.ncbi.nlm.nih.gov/pubmed/30458696 http://dx.doi.org/10.1080/22423982.2018.1546069 |
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