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Design, characterization and in vivo evaluation of nanostructured lipid carriers (NLC) as a new drug delivery system for hydrochlorothiazide oral administration in pediatric therapy

The hydrochlorothiazide (HCT) low solubility and permeability give rise to limited and variable bioavailability; its low stability makes it difficult to develop stable aqueous liquid formulations; its low dose makes the achievement of a homogeneous drug distribution very difficult. Thus, the aim of...

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Detalles Bibliográficos
Autores principales:	Cirri, Marzia, Maestrini, Lavinia, Maestrelli, Francesca, Mennini, Natascia, Mura, Paola, Ghelardini, Carla, Di Cesare Mannelli, Lorenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249610/ https://www.ncbi.nlm.nih.gov/pubmed/30451015 http://dx.doi.org/10.1080/10717544.2018.1529209

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