Species Specificity of Type III Interferon Activity and Development of a Sensitive Luciferase-Based Bioassay for Quantitation of Mouse Interferon-λ

The type III interferon (IFN-λ) family includes 4 IFN-λ subtypes in man. In the mouse, only the genes coding for IFN-λ2 and -λ3 are present. Unlike mouse and human type I IFNs (IFN-α/β), which exhibit strong species specificity, type III IFNs were reported to act in a cross-specific manner. We reexa...

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Detalles Bibliográficos
Autores principales: Jacobs, Sophie, Wavreil, Fanny, Schepens, Bert, Gad, Hans Henrik, Hartmann, Rune, Rocha-Pereira, Joana, Neyts, Johan, Saelens, Xavier, Michiels, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2018
Materias:
Research Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249671/
https://www.ncbi.nlm.nih.gov/pubmed/30335553
http://dx.doi.org/10.1089/jir.2018.0066

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