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Traumatic brain injury is associated with increased syndecan-1 shedding in severely injured patients

INTRODUCTION: Head injury and exsanguination are the leading causes of death in trauma patients. Hemorrhagic shock triggers systemic endothelial glycocalyx breakdown, potentially leading to traumatic endotheliopathy (EoT). Levels of syndecan-1, a main glycocalyx component, have been used to assess t...

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Detalles Bibliográficos
Autores principales: Gonzalez Rodriguez, Erika, Cardenas, Jessica C., Cox, Charles S., Kitagawa, Ryan S., Stensballe, Jakob, Holcomb, John B., Johansson, Pär I., Wade, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249764/
https://www.ncbi.nlm.nih.gov/pubmed/30463625
http://dx.doi.org/10.1186/s13049-018-0565-3