Myelolytic Treatments Enhance Oncolytic Herpes Virotherapy in Models of Ewing Sarcoma by Modulating the Immune Microenvironment

Ewing sarcoma is a highly aggressive cancer that promotes the infiltration and activation of pro-tumor M2-like macrophages. Oncolytic virotherapy that selectively infects and destroys cancer cells is a promising option for treating Ewing sarcoma. The effect of tumor macrophages on oncolytic virus th...

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Detalles Bibliográficos
Autores principales: Denton, Nicholas L., Chen, Chun-Yu, Hutzen, Brian, Currier, Mark A., Scott, Thomas, Nartker, Brooke, Leddon, Jennifer L., Wang, Pin-Yi, Srinivas, Rachelle, Cassady, Kevin A., Goins, William F., Cripe, Timothy P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249791/
https://www.ncbi.nlm.nih.gov/pubmed/30505937
http://dx.doi.org/10.1016/j.omto.2018.10.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249791/
https://www.ncbi.nlm.nih.gov/pubmed/30505937
http://dx.doi.org/10.1016/j.omto.2018.10.001

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