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Myelolytic Treatments Enhance Oncolytic Herpes Virotherapy in Models of Ewing Sarcoma by Modulating the Immune Microenvironment
Ewing sarcoma is a highly aggressive cancer that promotes the infiltration and activation of pro-tumor M2-like macrophages. Oncolytic virotherapy that selectively infects and destroys cancer cells is a promising option for treating Ewing sarcoma. The effect of tumor macrophages on oncolytic virus th...
Autores principales: | Denton, Nicholas L., Chen, Chun-Yu, Hutzen, Brian, Currier, Mark A., Scott, Thomas, Nartker, Brooke, Leddon, Jennifer L., Wang, Pin-Yi, Srinivas, Rachelle, Cassady, Kevin A., Goins, William F., Cripe, Timothy P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249791/ https://www.ncbi.nlm.nih.gov/pubmed/30505937 http://dx.doi.org/10.1016/j.omto.2018.10.001 |
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