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Extracellular vesicles transfer nuclear Abl-dependent and radiation-induced miR-34c into unirradiated cells to cause bystander effects
Ionizing radiation (IR) not only activates DNA damage response (DDR) in irradiated cells but also induces bystander effects (BE) in cells not directly targeted by radiation. How DDR pathways activated in irradiated cells stimulate BE is not well understood. We show here that extracellular vesicles s...
Autores principales: | Rastogi, Shubhra, Hwang, Amini, Chan, Josolyn, Wang, Jean Y. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249796/ https://www.ncbi.nlm.nih.gov/pubmed/29975106 http://dx.doi.org/10.1091/mbc.E18-02-0130 |
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