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Nde1 promotes diverse dynein functions through differential interactions and exhibits an isoform-specific proteasome association
Nde1 is a key regulator of cytoplasmic dynein, binding directly to both dynein itself and the dynein adaptor, Lis1. Nde1 and Lis1 are thought to function together to promote dynein function, yet mutations in each result in distinct neurodevelopment phenotypes. To reconcile these phenotypic differenc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The American Society for Cell Biology
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249811/ https://www.ncbi.nlm.nih.gov/pubmed/30024347 http://dx.doi.org/10.1091/mbc.E18-07-0418 |