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Upregulation of FOXM1 leads to diminished drug sensitivity in myeloma

BACKGROUND: Following up on previous work demonstrating the involvement of the transcription factor forkhead box M1 (FOXM1) in the biology and outcome of a high-risk subset of newly diagnosed multiple myeloma (nMM), this study evaluated whether FOXM1 gene expression may be further upregulated upon t...

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Detalles Bibliográficos
Autores principales: Gu, Chunyan, Jing, Xuefang, Holman, Carol, Sompallae, Ramakrishna, Zhan, Fenghuang, Tricot, Guido, Yang, Ye, Janz, Siegfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249818/
https://www.ncbi.nlm.nih.gov/pubmed/30463534
http://dx.doi.org/10.1186/s12885-018-5015-0