Roles of mitochondrial ROS and NLRP3 inflammasome in multiple ozone-induced lung inflammation and emphysema

BACKGROUND: Mitochondrial damage leading to oxidant stress may play an important role in the pathogenesis of airflow obstruction and emphysema. NLPR3 inflammasome can be activated by mitochondrial ROS (mtROS) and other stimuli. We examined the importance of mtROS and NLRP3 inflammasome and their int...

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Detalles Bibliográficos
Autores principales: Li, Feng, Xu, Mengmeng, Wang, Muyun, Wang, Lei, Wang, Hanying, Zhang, Hai, Chen, Yuqing, Gong, Jicheng, Zhang, Junfeng(Jim), Adcock, Ian M., Chung, Kian Fan, Zhou, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249848/
https://www.ncbi.nlm.nih.gov/pubmed/30466433
http://dx.doi.org/10.1186/s12931-018-0931-8

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