Cargando…
Central masked adjudication of stroke diagnosis at trial entry offered no advantage over diagnosis by local clinicians: Secondary analysis and simulation
BACKGROUND: Central adjudication of stroke type is commonly implemented in large multicentre clinical trials. We investigated the effect of central adjudication of diagnosis of stroke type at trial entry in the Efficacy of Nitric Oxide in Stroke (ENOS) trial. METHODS: ENOS recruited patients with ac...
Autores principales: | Godolphin, Peter J., Hepburn, Trish, Sprigg, Nikola, Walker, Liz, Berge, Eivind, Collins, Ronan, Gommans, John, Ntaios, George, Pocock, Stuart, Prasad, Kameshwar, Wardlaw, Joanna M., Bath, Philip M., Montgomery, Alan A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249966/ https://www.ncbi.nlm.nih.gov/pubmed/30533551 http://dx.doi.org/10.1016/j.conctc.2018.11.002 |
Ejemplares similares
-
Central adjudication of serious adverse events did not affect trial’s safety results: Data from the Efficacy of Nitric Oxide in Stroke (ENOS) trial
por: Godolphin, Peter J., et al.
Publicado: (2018) -
Outcome assessment by central adjudicators in randomised stroke trials: Simulation of differential and non-differential misclassification
por: Godolphin, Peter J, et al.
Publicado: (2020) -
Associations between change in blood pressure and functional outcome, early events and death: results from the Efficacy of Nitric Oxide in Stroke trial
por: Sandset, Else C., et al.
Publicado: (2019) -
Effect of Glyceryl Trinitrate on Hemodynamics in Acute Stroke: Data From the ENOS Trial
por: Appleton, Jason P., et al.
Publicado: (2019) -
Relationship between nitrate headache and outcome in patients with acute stroke: results from the efficacy of nitric oxide in stroke (ENOS) trial
por: Beishon, Lucy, et al.
Publicado: (2020)